ReviewCurrent pain and headache reports2012
Neuromuscular function in painful knee osteoarthritis.
Review in Current pain and headache reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02854176 (Somatosensory Electrical Stimulation to Improve Motor Control in Patients Suffering From Knee Osteoarthritis), which is not on this map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Somatosensory Electrical Stimulation to Improve Motor Control in Patients Suffering From Knee Osteoarthritis
Who cites it
14 citing papers in PubMed, 23 citations in OpenAlex.
- Increased motor cortex inhibition as a marker of compensation to chronic pain in knee osteoarthritis.Scientific reports · 2021Trial
- Acid-induced experimental knee pain and hyperalgesia in healthy humans.Experimental brain research · 2018Trial
- Knee pain and related health in the community study (KPIC): a cohort study protocol.BMC musculoskeletal disorders · 2017Trial
- Hip range of motion is differentially associated with pain sensitivity in individuals with and without knee osteoarthritis.BMC musculoskeletal disorders · 2026Article
- Neuromuscular Characteristics Associated with Knee Instability in Osteoarthritis and After Total Knee Replacement: A Systematic Review and Meta-Analysis.Clinics and practice · 2026Review
- Revisiting the Subtle Relationship Between Metabolic Syndrome and Osteoarthritis.Journal of inflammation research · 2026Review
- Adaptive Force of hamstring muscles is reduced in patients with knee osteoarthritis compared to asymptomatic controls.BMC musculoskeletal disorders · 2024Article
- EEG theta and beta bands as brain oscillations for different knee osteoarthritis phenotypes according to disease severity.Scientific reports · 2022Observational
- The beneficial role of companion animals in translational pain research.Frontiers in pain research (Lausanne, Switzerland) · 2022Review
- Comparison of Predisposing Factors Between Pain on Walking and Pain at Rest in Patients with Knee Osteoarthritis.Journal of pain research · 2021Article
- Comorbidity of Fibromyalgia in Primary Knee Osteoarthritis: Potential Impact on Functional Status and Quality of Life.Open access rheumatology : research and reviews · 2020Article
- Neuropathic-like knee pain and associated risk factors: a cross-sectional study in a UK community sample.Arthritis research & therapy · 2018Article
- Vitamin D status and pain sensitization in knee osteoarthritis: a critical review of the literature.Pain management · 2015Review
- Association of Mu opioid receptor (A118G) and BDNF (G196A) polymorphisms with rehabilitation-induced cortical inhibition and analgesic response in chronic osteoarthritis pain.International journal of clinical and health psychology : IJCHPArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pain is a major cause of impaired mobility in elderly patients with chronic osteoarthritis (OA) of the knee. Central sensitization and impaired nociceptive inhibitory mechanisms have both been identified as contributing factors to heightened pain in this patient population. While central sensitization has been shown to produce enhanced pain responses and spread of pain to adjacent and remote body regions, conditioned pain modulation has also been shown to be adversely affected, and may be characteristic of those patients with chronic pain. Alterations of quantitative sensory testing measures have been demonstrated in patients with knee OA, and may serve as a clinical means of staging chronic musculoskeletal pain, including assessment of hyperalgesia and hypoesthesia. In addition, pain and altered somatosensation commonly associated with OA may be correlated with functional deficits.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.