Evidence map›Paper›PMID 23054920›Full record

ReviewJournal of general internal medicine2013

Individualizing cancer screening in older adults: a narrative review and framework for future research.

Elizabeth Eckstrom, David H Feeny, Louise C Walter, Leslie A Perdue, Evelyn P Whitlock

Abstract readReview
In one paragraph

Review in Journal of general internal medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Does Messaging for Reducing Breast Cancer Overscreening in Older Women Have Differential Responses among Medical Minimizers and Maximizers?Medical decision making : an international journal of the Society for Medical Decision Making · 2026
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  11. Upper Gastrointestinal Endoscopy in Elderly Patients: An Individualized Decision-Making Approach for Screening and Surveillance.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elizabeth EckstromDepartment of Medicine, Division of General Internal Medicine & Geriatrics, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, L475, Portland, OR 97239, USA. eckstrom@ohsu.edu
David H Feeny
Louise C Walter
Leslie A Perdue
Evelyn P Whitlock

Funding

Prostate-Specific Antigen Practices and Outcomes in the ElderlyR01CA134425 · NCI · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI WALTER, LOUISE C. · 2009 to 2013
$1.7M
Midcareer Mentoring Award for Patient-Oriented Research in AgingK24AG041180 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WALTER, LOUISE C. · 2011 to 2016
$909k
NCI NIH HHS R01 CA134425NIA NIH HHS K24 AG041180NIA NIH HHS K24AG041180
6 · The paper itself

Abstract

Older adults often have multiple chronic conditions that may decrease additional life expectancy. Research evaluating the benefits and harms of screening must include consideration of competing morbidities and patient heterogeneity (beyond age), potentially increased harms of screening, and patient preferences. Other areas in need of additional research include the lack of evidence for older adults on the harms of screening tests; the overdiagnosis of disease; the burden of disease labeling; the effects of inaccurate test results; the harms of disease treatment; and harms related to prioritization of healthcare (e.g., for a particular patient, lifestyle counseling may be more important than screening). Nontraditional outcomes, such as the effects on family caregivers, are also relevant. Studies comparing trajectories of quality-adjusted survival with and without screening to assess net benefit are typically lacking. There is little evidence on the preferences of older adults for deciding whether to be screened, the process of being screened, and the health states associated with being or not being screened. To enhance the quality and quantity of evidence, older adults need to be enrolled in screening trials and clinical studies. Measures of functional status and health-related quality of life (HRQL) need to be included in trials, registries, and cohort studies. This article addresses these challenges, and presents a framework for what research is needed to better inform screening decisions in older adults.

Indexed as

AgedAge FactorsBiomedical ResearchEarly Detection of CancerHealth Services for the AgedHumansOutcome Assessment, Health CarePatient PreferencePractice Guidelines as Topic

Identifiers

PMID23054920
PMCPMC3614148

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.