Evidence map›Paper›PMID 23054625›Full record

ReviewCurrent allergy and asthma reports2012

Cellular targeting in autoimmunity.

Jennifer L Rogers, Donald S Serafin, Roman G Timoshchenko, Teresa K Tarrant

Abstract readReview
In one paragraph

Review in Current allergy and asthma reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. G protein signaling modulator-3: a leukocyte regulator of inflammation in health and disease.American journal of clinical and experimental immunology · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jennifer L RogersDivision of Rheumatology, Allergy, and Immunology and the Thurston Arthritis Research Center, University of North Carolina School of Medicine, Chapel Hill, NC 27517, USA.
Donald S Serafin
Roman G Timoshchenko
Teresa K Tarrant
University of North Carolina at Chapel Hill · US

Funding

G protein-coupled receptor kinase 3 regulation of leukocyte function in inflammatR03AR059286 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI TARRANT, TERESA KATHLEEN · 2011 to 2013
$218k
NIAMS NIH HHS R03 AR059286
6 · The paper itself

Abstract

Many biologic agents that were first approved for the treatment of malignancies are now being actively investigated and used in a variety of autoimmune diseases such as rheumatoid arthritis (RA), antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis, systemic lupus erythematosus (SLE), and Sjogren's syndrome. The relatively recent advance of selective immune targeting has significantly changed the management of autoimmune disorders and in part can be attributed to the progress made in understanding effector cell function and their signaling pathways. In this review, we will discuss the recent FDA-approved biologic therapies that directly target immune cells as well as the most promising investigational drugs affecting immune cell function and signaling for the treatment of autoimmune disease.

Indexed as

AnimalsAntibodies, Monoclonal, Murine-DerivedAntineoplastic AgentsArthritis, RheumatoidAutoimmune DiseasesAutoimmunityBiological TherapyB-LymphocytesHumansImmunity, CellularImmunosuppressive AgentsLupus Erythematosus, SystemicProtein-Tyrosine KinasesRituximabSjogren's SyndromeT-LymphocytesAntibodies, Monoclonal, Murine-DerivedAntineoplastic AgentsImmunosuppressive AgentsProtein-Tyrosine KinasesRituximab

Identifiers

PMID23054625
PMCPMC3493824
OpenAlexW2061075934

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.