ArticleIrish journal of medical science2013
A multicentre analysis of troponin use in clinical practice.
Article in Irish journal of medical science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Facility Variation in Troponin Ordering Within the Veterans Health Administration.Medical care · 2020Article
- Troponin Testing in the Emergency Department: Real world experience.Sultan Qaboos University medical journal · 2017Article
- Appropriate pathology ordering? Troponin testing within an Australian Emergency Department.Irish journal of medical science · 2017Article
- Transitioning high sensitivity cardiac troponin I (hs-cTnI) into routine diagnostic use: More than just a sensitivity issue.Practical laboratory medicine · 2016Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe role of troponin quantification in evaluation of patients with suspected acute coronary syndrome is established, but with cost implications. Emerging high-sensitivity troponin and novel multi-marker assays herald further resource implications.
aimsThe objective of this study was to quantify recent trends in troponin usage and costs in a cross-section of hospitals.
methodsA cross-sectional survey seeking data on troponin usage and costs from six tertiary referral, public access teaching hospitals for consecutive years between 2003 and 2009 was carried out.
resultsA median annual increase in the volume of troponin assays requested was identified in all six hospitals, with an average median annual increase of 6.9 % across hospitals (interquartile range 3.4, 10.1 %). This annual increase was not accompanied by a corresponding increase in volume of patients presenting to the Emergency Department (ED) with chest pain. The majority (44-67 %) of troponin requests originated in the ED of hospitals. The median annual spend on troponins per hospital was <euro>115,612 (interquartile range <euro>80,452, <euro>140,918). An analysis of results of assays performed in one centre found that the majority (91 %) of troponin assays performed were in the normal range.
conclusionsAn annual increase in troponin requests without a corresponding increase in patient activity raises the possibility of increasingly indiscriminate troponin testing. The cumulative direct and indirect costs of inappropriate testing are significant. Corrective strategies are necessary to improve patient selection and testing protocols, particularly in the advent of the high-sensitivity troponin assays and novel multi-marker strategies.
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