ReviewHeart failure reviews2013
Cardiomyocyte autophagy: metabolic profit and loss.
Review in Heart failure reviews, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 42 citations in OpenAlex.
- The potential of targeting autophagy-related non-coding RNAs in the treatment of lung cancer.Frontiers in pharmacology · 2025Review
- Large animal models of pressure overload-induced cardiac left ventricular hypertrophy to study remodelling of the human heart with aortic stenosis.Cardiovascular research · 2024Review
- Deficiency of diacylglycerol Kinase ζ promotes Beclin1-mediated autophagyInternational journal of medical sciences · 2024Article
- The AP-1 Transcription Factor Fosl-2 Regulates Autophagy in Cardiac Fibroblasts during Myocardial Fibrogenesis.International journal of molecular sciences · 2021Article
- MMP9 inhibition increases autophagic flux in chronic heart failure.American journal of physiology. Heart and circulatory physiology · 2020Article
- Autophagy Activation in Zebrafish Heart Regeneration.Scientific reports · 2020Article
- The Class III PI3K/Beclin-1 Autophagic Pathway Participates in the mmLDL-Induced Upregulation of ETAdvances in pharmacological and pharmaceutical sciences · 2020Article
- Rapamycin Treatment Reduces Acute Myocarditis Induced by Trypanosoma cruzi Infection.Journal of innate immunity · 2020Article
- The role of autophagy in cardiac hypertrophy.Acta biochimica et biophysica Sinica · 2016Review
- Chronic heart failure: Ca(2+), catabolism, and catastrophic cell death.Biochimica et biophysica acta · 2016Review
- Inhibition of hypertrophy is a good therapeutic strategy in ventricular pressure overload.Circulation · 2015Review
- Molecular mechanisms of autophagy in the cardiovascular system.Circulation research · 2015Review
- Article
- Carboxyl terminus of Hsp70-interacting protein (CHIP) is required to modulate cardiac hypertrophy and attenuate autophagy during exercise.Cell biochemistry and function · 2013Article
- Genetics and epigenetics of arrhythmia and heart failure.Frontiers in genetics · 2013Review
- Cardiac metabolism and its interactions with contraction, growth, and survival of cardiomyocytes.Circulation research · 2013Review
- Hypertrophic reprogramming of the left ventricle: translation to the ECG.Journal of electrocardiologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Cardiovascular disease remains the leading cause of morbidity and mortality worldwide, even despite recent scientific and technological advances and comprehensive preventive strategies. The cardiac myocyte is a voracious consumer of energy, and alterations in metabolic substrate availability and consumption are hallmark features of these disorders. Autophagy, an evolutionarily ancient response to metabolic insufficiency, has been implicated in the pathogenesis of a wide range of heart pathologies. However, the precise role of autophagy in these contexts remains obscure owing to its multifarious actions. Here, we review recently derived insights regarding the role of autophagy in cardiac hypertrophy and heart failure, highlighting its effects on metabolism.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.