ArticleJournal of bioenergetics and biomembranes2013
Mitochondrial haplotype divergences affect specific temperature sensitivity of mitochondrial respiration.
Article in Journal of bioenergetics and biomembranes, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 46 citations in OpenAlex.
- Mitonuclear Coevolution in Bumblebees (Bombus): Genomic Signatures and Its Role in Climatic Niche Adaptation.Genome biology and evolution · 2025Article
- Asymmetric mitonuclear interactions trigger transgressive inheritance and mitochondria-dependent heterosis in hybrids of the model systemIMA fungus · 2025Article
- Temperature-dependent benefits and costs of cytoplasmic male sterility in snailProceedings. Biological sciences · 2025Article
- How Does Mitochondrial Protein-Coding Gene Expression inAnimals : an open access journal from MDPI · 2023Article
- Mitochondrial gene expression in different organs of Hoplobatrachus rugulosus from China and Thailand under low-temperature stress.BMC zoology · 2022Article
- Temperature-Specific and Sex-Specific Fitness Effects of Sympatric Mitochondrial and Mito-Nuclear Variation inInsects · 2022Article
- Flexible Thermal Sensitivity of Mitochondrial Oxygen Consumption and Substrate Oxidation in Flying Insect Species.Frontiers in physiology · 2022Article
- Positive selection on two mitochondrial coding genes and adaptation signals in hares (genus Lepus) from China.BMC ecology and evolution · 2021Article
- Mechanical Permeabilization as a New Method for Assessment of Mitochondrial Function in Insect Tissues.Methods in molecular biology (Clifton, N.J.) · 2021Article
- The Role of Mitonuclear Incompatibility in Bipolar Disorder Susceptibility and Resilience Against Environmental Stressors.Frontiers in genetics · 2021Review
- Adjustments of cardiac mitochondrial phenotype in a warmer thermal habitat is associated with oxidative stress in European perch, Perca fluviatilis.Scientific reports · 2020Article
- An experimental test of temperature-dependent selection on mitochondrial haplotypes inEcology and evolution · 2020Article
- Thermal tolerance and fish heart integrity: fatty acids profiles as predictors of species resilience.Conservation physiology · 2020Article
- Mitochondrial DNA and temperature tolerance in lager yeasts.Science advances · 2019Article
- Energy demand and the context-dependent effects of genetic interactions underlying metabolism.Evolution letters · 2018Article
- Mitochondrial function and bioenergetic trade-offs during lactation in the house mouse (Ecology and evolution · 2017Article
- Heterogeneous natural selection on oxidative phosphorylation genes among fishes with extreme high and low aerobic performance.BMC evolutionary biology · 2015Article
- Positive selection in development and growth rate regulation genes involved in species divergence of the genus Radix.BMC evolutionary biology · 2015Article
- Article
- Mitochondrial-nuclear epistasis contributes to phenotypic variation and coadaptation in natural isolates of Saccharomyces cerevisiae.Genetics · 2014Article
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
The aim of this study was to investigate the effect of temperature changes on the functional properties of mitochondria from two sets of D. simulans fly lines harboring the siII and siIII haplotypes in a common nuclear genetic background. We studied four introgressed isofemale lines possessing the mtDNA of siII and the nuclear background of siIII (siII-introgressed) and four lines possessing siIII mitochondria with its native nuclear genome (siIII-controls). We assessed the catalytic capacities of electron transport system (ETS) at four different temperatures (12, 18, 24 and 28 ºC). The impact of temperature on the pyruvate dehydrogenase (PDH) activity, the mitochondrial respiration (coupled and uncoupled respiration), cytochrome c oxidase activity, as well as the excess capacity of complex IV (COX) were evaluated in these two sets of flies. Our results showed that the temperature coefficient values (Q(10)) measured for mitochondrial respiration in the lower range of temperatures (12 to 18 ºC) showed a 2 to 3 fold increase in siII-introgressed when compared to siIII-controls. This result shows that the impact of temperature on mitochondrial function is different between the two mitotypes studied. The Q(10) results seem to be linked to the apparent COX excess capacity of 193% for siIII-controls that is inexistent for siII-introgressed at 12 ºC. One explanation for these results is that the mitochondria can compensate for the disruption of mito-nuclear interactions at 24 ºC but not at lower temperatures. An alternate explanation would be that siII haplotype confer divergent kinetic properties to the ETS that translate to different temperature sensitivities.
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