ArticleJournal of materials science. Materials in medicine2013
Electrospun polycaprolactone scaffolds with tailored porosity using two approaches for enhanced cellular infiltration.
Article in Journal of materials science. Materials in medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 58 citations in OpenAlex.
- Cell Adhesion and Local Cytokine Control on Protein-Functionalized PNIPAM-co-AAc Hydrogel Microcarriers.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Electrospun poly(lactic acid) membranes with defined pore size to enhance cell infiltration.Heliyon · 2024Article
- Electrospun Polycaprolactone Membranes Expanded with Chitosan Granules for Cell Infiltration.Polymers · 2024Article
- Review
- Review
- Fabrication of PCL nanofibrous scaffold with tuned porosity for neural cell culture.Progress in biomaterials · 2021Article
- Tailored PCL Scaffolds as Skin Substitutes Using Sacrificial PVP Fibers and Collagen/Chitosan Blends.International journal of molecular sciences · 2020Article
- The improvement of cell infiltration in an electrospun scaffold with multiple synthetic biodegradable polymers using sacrificial PEO microparticles.Journal of biomedical materials research. Part A · 2019Article
- Strategies to Tune Electrospun Scaffold Porosity for Effective Cell Response in Tissue Engineering.Journal of functional biomaterials · 2019Review
- Long-Term Functional Efficacy of a Novel Electrospun Poly(Glycerol Sebacate)-Based Arterial Graft in Mice.Annals of biomedical engineering · 2016Article
- Electrospun polyurethane as an alternative ventricular catheter and in vitro model of shunt obstruction.Journal of biomaterials applications · 2015Article
- A hypothesis-driven parametric study of effects of polymeric scaffold properties on tissue engineered neovessel formation.Acta biomaterialia · 2015Article
- Photoactive Electrospun Polymeric Meshes: Spatiotemporally Wetting of Textured 3-Dimensional Structures.Journal of materials chemistry. B · 2014Article
- Improved cellular infiltration in electrospun fiber via engineered porosity.Tissue engineering · 2007Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The impact of mat porosity of polycaprolactone (PCL) electrospun fibers on the infiltration of neuron-like PC12 cells was evaluated using two different approaches. In the first method, bi-component aligned fiber mats were fabricated via the co-electrospinning of PCL with polyethylene oxide (PEO). Variation of the PEO flow rate, followed by selective removal of PEO from the PCL/PEO mesh, allowed for control of the porosity of the resulting scaffold. In the second method, aligned fiber mats were fabricated from various concentrations of PCL solutions to generate fibers with diameters between 0.13 ± 0.06 and 9.10 ± 4.1 μm. Of the approaches examined, the variation of PCL fiber diameter was found to be the better method for increasing the infiltration of PC12 cells, with the optimal infiltration into the ca. 1.5-mm-thick meshes observed for the mats with the largest fiber diameters, and hence largest pore sizes.
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