ArticleThe American journal of clinical nutrition2012
Prospective cohort study of tea consumption and risk of digestive system cancers: results from the Shanghai Women's Health Study.
Article in The American journal of clinical nutrition, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 12 of them syntheses that pooled it.
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Who cites it
39 citing papers in PubMed, 12 syntheses or guidelines pooled it, 86 citations in OpenAlex.
- Dietary factors and colorectal cancer risk in Asian populations: a systematic review and meta-analysis of cohort studies.Cancer causes & control : CCC · 2025Pooled it
- Hot Tea Consumption and Esophageal Cancer Risk: A Meta-Analysis of Observational Studies.Frontiers in nutrition · 2022Pooled it
- Tea consumption and colorectal cancer risk: a meta-analysis of prospective cohort studies.European journal of nutrition · 2020Pooled it
- Green tea (Camellia sinensis) for the prevention of cancer.The Cochrane database of systematic reviews · 2020Pooled it
- Pooled it
- Association between green tea intake and risk of gastric cancer: a systematic review and dose-response meta-analysis of observational studies.Public health nutrition · 2017Pooled it
- Tea consumption and the risk of biliary tract cancer: a systematic review and dose-response meta-analysis of observational studies.Oncotarget · 2017Pooled it
- Pooled it
- Liver-related safety assessment of green tea extracts in humans: a systematic review of randomized controlled trials.European journal of clinical nutrition · 2016Pooled it
- Association between Genetic Polymorphisms in DEFB1 and Susceptibility to Digestive Diseases.Medical science monitor : international medical journal of experimental and clinical research · 2015Pooled it
- Pooled it
- Tea consumption and the risk of five major cancers: a dose-response meta-analysis of prospective studies.BMC cancer · 2014Pooled it
- Exploring the anticancer potential of epigallocatechin gallate-loaded sodium alginate nanoparticles: impact of size variation on head and neck cancer cells.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Article
- Early-onset and later-onset cancer: trends, risk factors, and prevention in Northern China.Science China. Life sciences · 2024Article
- Cumulative consumption of tea is associated with lower risk of liver cancer: Updated results from the Shanghai Women's Health Study.International journal of cancer · 2023Article
- Consumption of Coffee and Green Tea and the Risk of Colorectal Cancer in Korea: The Health Examinees Study.Journal of cancer prevention · 2022Article
- Improvement of postoperative quality of life in patients with esophageal squamous cell carcinoma: does tea consumption have a role?BMC public health · 2022Article
- Association of Ginseng Consumption With All-cause and Cause-specific Mortality: Shanghai Women's Health Study.Journal of epidemiology · 2022Article
- Anticarcinogenic potentials of tea catechins.Frontiers in nutrition · 2022Review
- A Prospective Investigation of Circulating Metabolome Identifies Potential Biomarkers for Gastric Cancer Risk.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021Article
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
backgroundData from in vitro and animal studies support a protective role for tea in the etiology of digestive system cancers; however, results from prospective cohort studies have been inconsistent. In addition, to our knowledge, no study has investigated the association of tea consumption with the incidence of all digestive system cancers in Chinese women.
objectiveWe investigated the association of regular tea intake (≥3 times/wk for >6 mo) with risk of digestive system cancers.
designWe used the Shanghai Women's Health Study, a population-based prospective cohort study of middle-aged and older Chinese women who were recruited in 1996-2000. Adjusted HRs and associated 95% CIs were derived from Cox regression models.
resultsAfter a mean follow-up of 11 y, 1255 digestive system cancers occurred (stomach, esophagus, colorectal, liver, pancreas, and gallbladder/bile duct cancers) in 69,310 nonsmoking and non-alcohol-drinking women. In comparison with women who never drank tea, regular tea intake (mostly green tea) was associated with reduced risk of all digestive system cancers combined (HR: 0.86; 95% CI: 0.74, 0.98), and the reduction in risk increased as the amount and years of tea consumption increased (P-trend = 0.01 and P-trend < 0.01, respectively). For example, women who consumed ≥150 g tea/mo (∼2-3 cups/d) had a 21% reduced risk of digestive system cancers combined (HR: 0.79; 95% CI: 0.63, 0.99). The inverse association was found primarily for colorectal and stomach/esophageal cancers.
conclusionIn this large prospective cohort study, tea consumption was associated with reduced risk of colorectal and stomach/esophageal cancers in Chinese women.
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