Evidence map›Paper›PMID 23053517›Full record

ArticleArchives of virology2013

No novel coronaviruses identified in a large collection of human nasopharyngeal specimens using family-wide CODEHOP-based primers.

Kalina T Zlateva, Frank E J Coenjaerts, Kelly M Crusio, Christine Lammens, Frank Leus, Marco Viveen, Margareta Ieven, Willy J M Spaan, Eric C J Claas, Alexander E Gorbalenya

Open access · bronzeAbstract readEvaluation Study
In one paragraph

Article in Archives of virology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Molecular Diagnosis of Coronavirus Disease 2019.Critical care explorations · 2020
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Kalina T ZlatevaDepartment of Medical Microbiology, Leiden University Medical Center, Albinusdreef 2, E4-P, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.
Frank E J Coenjaerts
Kelly M Crusio
Christine Lammens
Frank Leus
Marco Viveen
Margareta Ieven
Willy J M Spaan
Eric C J Claas
Alexander E Gorbalenya
Leiden University Medical Center · NLUniversity Medical Center Utrecht · NLAntwerp University Hospital · BEUniversity of Antwerp · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel viruses might be responsible for numerous disease cases with unknown etiology. In this study, we screened 1800 nasopharyngeal samples from adult outpatients with respiratory disease symptoms and healthy individuals. We employed a reverse transcription (RT)-PCR assay and CODEHOP-based primers (CT12-mCODEHOP) previously developed to recognize known and unknown corona- and toroviruses. The CT12-mCODEHOP assay detected 42.0 % (29/69) of samples positive for human coronaviruses (HCoV), including HCoV-229 (1/16), HCoV-NL63 (9/17), and HCoV-OC43 (19/36), and additionally HCoV-HKU1 (3), which was not targeted by the diagnostic real-time PCR assays. No other coronaviruses were identified in the analyzed samples.

Indexed as

CoronavirusDNA PrimersHumansNasopharynxRespiratory Tract InfectionsReverse Transcriptase Polymerase Chain ReactionDNA Primers

Identifiers

PMID23053517
PMCPMC7087030
OpenAlexW2136717520

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.