Evidence map›Paper›PMID 23053218›Full record

ArticleArchives of women's mental health2012

Proof of concept: Partner-Assisted Interpersonal Psychotherapy for perinatal depression.

Anna R Brandon, Nadia Ceccotti, Linda S Hynan, Geetha Shivakumar, Neysa Johnson, Robin B Jarrett

Registry-linked trialAbstract read
In one paragraph

Article in Archives of women's mental health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01732055 (Partner-Assisted Interpersonal Psychotherapy or Antidepressant Medication for Antenatal Depression), which is not on this map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01732055 phase1 / phase2terminatednot on this map

Partner-Assisted Interpersonal Psychotherapy or Antidepressant Medication for Antenatal Depression

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2012 to 2013Enrolled2ConditionsPartner Assisted Interpersonal Psychotherapy, Treatment as UsualArmsPartner-Assisted Interpersonal Psychotherapy, Treatment as Usual
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Interpersonal Psychotherapy to Reduce Psychological Distress in Perinatal Women: A Systematic Review.International journal of environmental research and public health · 2020
    Pooled it
  2. Pooled it
  3. ABM Clinical Protocol #18: Use of Antidepressants in Breastfeeding Mothers.Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine
    Guideline
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anna R BrandonDepartment of Psychiatry, Women's Mood Disorders Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. anna_brandon@med.unc.edu.
Nadia Ceccotti
Linda S Hynan
Geetha Shivakumar
Neysa Johnson
Robin B Jarrett

Funding

NORTH AND CENTRAL TEXAS CTSA FOR PEDIATRIC RESEARCHUL1RR024982 · NCRR · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2007 to 2011
$27.9M
North and Central Texas Clinical and Translational Science Initiative (KL2)KL2RR024983 · NCRR · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2007 to 2011
$4.3M
Cognitive Therapy for High Risk &Refractory DepressionK24MH001571 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI JARRETT, ROBIN B · 2005 to 2009
$625k
Partner-Assisted Therapy for the Treatment of Depression During PregnancyK23MH085007 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI BRANDON, ANNA R · 2009 to 2011
$385k
NCRR NIH HHS KL2 RR024983NCRR NIH HHS KL2RR024983NCRR NIH HHS UL1 RR024982NIMH NIH HHS K23 MH085007NIMH NIH HHS K23MH085007NIMH NIH HHS K24 MH001571NIMH NIH HHS K24-MH001571NIMH NIH HHS L30 MH084635
6 · The paper itself

Abstract

Although poor partner support is a key risk factor for depression in pregnant and postpartum women, partners are not generally involved in treatment beyond psychoeducation. The aim of this "proof of concept" study was to test safety, acceptability, and feasibility of Partner-Assisted Interpersonal Psychotherapy (PA-IPT), an intervention that includes the partner as an active participant throughout treatment. Women more than 12 weeks estimated gestational age and less than 12 weeks postpartum were invited to participate if they fulfilled DSM-IV criteria for Major Depressive Disorder and reported moderate symptom severity (HAM-D(17) ≥16). The open trial included eight acute-phase sessions and a 6-week follow-up assessment. Ten couples completed the acute phase treatment and nine presented for a 6-week follow-up assessment. There were no study-related adverse events, and no women had symptomatic worsening from intake to Session Eight. All partners attended all sessions, no couples dropped out of treatment, and all reported positive treatment satisfaction at the conclusion of the study. Nine of ten women (90 %) met the criteria for clinical response (HAM-D(17) = 9) at the conclusion of acute phase treatment, and eight of the nine (89 %) presenting at a 6-week follow-up assessment met criteria for symptomatic recovery. Incorporating partners in the treatment of major depressive disorders during the perinatal period is safe, acceptable, and feasible, but needs further testing in a larger population to evaluate efficacy.

Indexed as

Interpersonal RelationsAdultDepressionDiagnostic and Statistical Manual of Mental DisordersFeasibility StudiesFemaleHumansMaleMothersPatient Acceptance of Health CarePregnancyPregnancy Trimester, FirstPrenatal CarePrevalencePsychotherapySexual Partners

Identifiers

PMID23053218
PMCPMC3495994

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.