ArticleStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2012
Metastatic spinal cord compression in patients with cancer of unknown primary. Estimating the survival prognosis with a validated score.
Article in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 28 citations in OpenAlex.
- Does Duration of Symptoms in Metastatic Spine Disease Affect Recovery and Outcomes? A Systematic Review and Meta-Analysis.Global spine journal · 2026Review
- Prediction of Survival Prognosis for Spinal Metastasis From Cancer of Unknown Primary: Derivation and Validation of a Nomogram Model.Global spine journal · 2024Article
- Review
- First statement on preparation for the COVID-19 pandemic in large German Speaking University-based radiation oncology departments.Radiation oncology (London, England) · 2020Review
- Classification and scoring systems for metastatic spine tumors: a literature review.Spine surgery and related research · 2017Review
- Variation in Practice Patterns of Korean Radiation Oncologists for Spine Metastasis between 2009 and 2014.Cancer research and treatment · 2016Article
- Inpatient rehabilitation outcomes in patients with malignant spinal cord compression compared to other non-traumatic spinal cord injury: A population based study.The journal of spinal cord medicine · 2015Article
- Long-term safety and efficacy of fractionated stereotactic body radiation therapy for spinal metastases.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2014Article
- Metastatic spinal cord compression: a validated survival score for elderly patients.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2014Article
- Scoring system for prediction of metastatic spine tumor prognosis.World journal of orthopedics · 2014Review
- Metastatic spinal cord compression as a result of the unknown primary tumour.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2014Article
- A new prognostic factor for the survival of patients with renal cell carcinoma developing metastatic spinal cord compression.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2014Article
- [Radiotherapeutic concepts in cancer of unknown primary site].Der Radiologe · 2014Review
- A validated scoring system to identify long-term survivors after radiotherapy for metastatic spinal cord compression.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2013Article
- Validation of a Survival Score for Patients Receiving Radiosurgery or Fractionated Stereotactic Radiotherapy for 1 to 3 Brain Metastases.In vivo (Athens, Greece)Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to create and validate a survival score for patients with metastatic spinal cord compression (MSCC) from cancer of unknown primary. PATIENTS AND
methodsThe entire cohort (n = 182) was divided into a test group (n = 91) and a validation group (n = 91). In the test group, eight pretreatment factors including age, gender, Eastern Cooperative Oncology Group performance status (ECOG-PS), number of involved vertebrae, ambulatory status, other bone metastases, visceral metastases, and time of developing motor deficits were retrospectively analyzed.
resultsThe score included the prognostic factors that were significant for survival in the multivariate analysis (ECOG-PS, ambulatory status, visceral metastases, time of developing motor deficits). The score for each factor was determined by dividing the 6-month survival rate by 10. Prognostic scores represented the sum of the scores for the four factors and ranged from 5 to 20 points. The 6-month survival rates were 5% for < 14 points, 41% for 14-16 points, and 92% for > 16 points (p < 0.001). In the validation group, the 6-month survival rates were 7%, 38%, and 91% (p < 0.001).
conclusionThis survival score can be considered valid and reproducible, since the survival rates of the validation group were comparable to those of the test group. This score can help when selecting the individual treatment and when counseling patients and relatives.
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Registered trials
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