ArticleJournal of cancer research and clinical oncology2013
Is helical tomotherapy accurate and safe enough for spine stereotactic body radiotherapy?
Article in Journal of cancer research and clinical oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Single-fraction IMRT Versus External Beam Radiotherapy for Patients With Spine Bone Metastases
Intensity-modulated Radiotherapy With Integrated-boost in Patients With Spinal Bone Metastases
Image-guided and Intensity-modulated Radiotherapy Versus External Beam Radiotherapy for Patients With Spine Metastases
Who cites it
6 citing papers in PubMed, 15 citations in OpenAlex.
- Trial
- Trial
- Comparison of setup accuracy and efficiency between the Klarity system and BodyFIX system for spine stereotactic body radiation therapy.Journal of applied clinical medical physics · 2022Observational
- Practical aspects of the application of helical tomotherapy for craniospinal irradiation.Scientific reports · 2021Article
- Article
- Phase I dose escalation study of helical intensity-modulated radiotherapy-based stereotactic body radiotherapy for hepatocellular carcinoma.Oncotarget · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe assessed the accuracy and safety of spine stereotactic body radiation therapy (SBRT) using helical tomotherapy (HT) via evaluating intrafractional patient movement.
methodsFrom July 2009 to April 2011, 22 patients with spine lesions received SBRT using HT, with a total of 61 fractions. To evaluate intrafractional movement, we compared post-treatment megavoltage CT scans with planning CT images and obtained translational [lateral (X), craniocaudal (Y), anterioposterior (Z)] offsets and total displacements (R). We analyzed the correlation of intrafractional motion with patient and treatment characteristics. We also analyzed dosimetric change to the target and spinal cord, resulting from intrafractional movement, in the three patients that showed the greatest R values.
resultsIntrafractional movements were 0.7 ± 0.6 mm (X), 1.1 ± 0.7 mm (Y), 0.9 ± 0.6 mm (Z), and 1.8 ± 0.6 mm (R). This movement did not correlate with age, pain score, treatment time, or treatment site. Only patients with lower BMIs have a tendency to move more during treatment. Patient immobilization using wrapping form (thermoplastic mask and BodyFIX(®) system) resulted in less lateral movement and total displacement than others (0.498 ± 0.409 vs. 1.138 ± 0.637 mm, P < 0.001 for X; and 1.638 ± 0.691 vs. 1.976 ± 0.495 mm, P = 0.032 for R). However, this intrafractional motion did not affect the dose delivery to the target and spinal cord.
conclusionSBRT using HT can be a safe treatment modality for spine metastasis with enhanced targeting accuracy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.