ArticleSurgical endoscopy2013
Correlation of the gastroesophageal flap valve grade with the surgery rate in patients with gastroesophageal reflux disease.
Article in Surgical endoscopy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Esophagogastric Junction Morphology on Hill's Classification Predicts Gastroesophageal Reflux with Good Accuracy and Consistency.Digestive diseases and sciences · 2021Pooled it
- Clinical characteristics and esophageal motility in patients with gastric cardia submucosal tumors and associated changes after endoscopic resection.Surgical endoscopy · 2025Article
- Association of gastroesophageal junction laxity and gastroesophageal reflux disease.Surgical endoscopy · 2024Article
- Value of endoscopic grading of gastroesophageal flap valve in gastroesophageal reflux disease.Surgical endoscopy · 2024Article
- Endoscopic Prediction for Acid Reflux in Patients without Hiatus Hernia.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2020Article
- Reflux finding score is associated with gastroesophageal flap valve status in patients with laryngopharyngeal reflux disease: a retrospective study.Scientific reports · 2019Article
- Abnormal Gastroesophageal Flap Valve Is Associated With High Gastresophageal Reflux Disease Questionnaire Score and the Severity of Gastroesophageal Reflux Disease in Vietnamese Patients With Upper Gastrointestinal Symptoms.Journal of neurogastroenterology and motility · 2018Article
- Analysis of computed tomographic findings according to gastroesophageal flap valve grade.The Korean journal of internal medicine · 2018Article
- Higher incidence of gastroesophageal reflux disease after gastric wedge resections of gastric submucosal tumors located close to the gastroesophageal junction.Annals of surgical treatment and research · 2014Article
- Impacts of endoscopic gastroesophageal flap valve grading on pediatric gastroesophageal reflux disease.PloS one · 2014Article
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Authors and funding
1 author at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe importance of endoscopic evaluation and grading of the gastroesophageal flap valve (GEFV) in patients with gastroesophageal reflux disease (GERD) was previously demonstrated with increased acid exposure and high grades of esophagitis in those with high-grade valves. On the other hand, no data exist on the relationship between GEFV appearance and surgical rate.
methodsFor 453 patients with symptoms suggestive of GERD, GEFV grading and 24-h ambulatory pH monitoring were performed. Surgery was performed for 82 of these patients who failed medical management or had disease complications.
resultsThe GEFV grade 4 patients were younger than the patients with normal GEFV (grades 1 [p = 0.017] and 2 [p < 0.001]) and showed significant male predominance. The prevalence of hiatal hernia, the degree of esophageal acid exposure, and the prevalence and degree of erosive esophagitis significantly increased with GEFV grade (p < 0.001 for all). No GEFV grade 1 patients underwent surgery compared with 4.9 % of the grade 2 patients, 20.5 % of the grade 3 patients, and 63.6 % of the grade 4 patients who had surgery for various indications (p < 0.001).
conclusionsEsophagogastric opening estimated by endoscopic grading of the GEFV was strongly correlated with surgery rate in GERD patients. In particular, patients with grade 4 valves showed the highest rates of erosive esophagitis and axial hiatal hernia and frequently underwent surgery for either failed medical management or disease complications.
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