ArticleZeitschrift fur Rheumatologie2013
[Regression of peripheral and pulmonary rheumatoid nodules under therapy with rituximab].
Article in Zeitschrift fur Rheumatologie, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 16 citations in OpenAlex.
- Article
- Cavitary pulmonary rheumatoid nodules in a patient on leflunomide: A case report.Radiology case reports · 2024Article
- Outcomes and Complications of Corticosteroid Injection of Rheumatoid Nodules.The Journal of clinical and aesthetic dermatology · 2022Article
- Treatment with biologic DMARDs may not adversely affect lung nodules in rheumatoid arthritis patients.European journal of rheumatology · 2022Article
- Not All Pulmonary Nodules in Smokers are Lung Cancer.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2021Article
- Rheumatoid lung nodules with "feeding-vessel" sign.Clinical rheumatology · 2021Review
- Complicated Rheumatoid Nodules in Lung.Case reports in rheumatology · 2020Article
- Multiple pulmonary rheumatoid nodules.Reumatologia · 2015Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report on a retrospective study of 16 rheumatoid arthritis (RA) patients with reduction in size of pulmonary and peripheral rheumatoid nodules following treatment with rituximab (RTX). The 8 female and 8 male patients had an average disease duration of 12.2 years, 88 % were anti-CCP positive and 94 % seropositive. Prior treatment included an average of 2.9 DMARD and 1.4 biological therapies. On average 6.1 rheumatoid nodules were found on hands and elbows and 5 patients had pulmonary nodules. In 6 out of 16 patients the nodules disappeared completely, in 2 patients a pulmonary nodule disappeared. In 10 out of 16 patients the size of the nodules decreased by approximately 50%, 1 out of the 16 patients with significant increase in size and number of nodules prior to RTX therapy showed a reduction in size but no new nodules occurred. The regression in size of the nodules occurred 34.2±39.1 weeks following RTX therapy, correlating with 1.3±0.59 RTX infusion cycles. Overall, increases in size or new nodules were reported in none of the patients. One nodule examined histologically following RTX therapy did not show any specific differences. RTX may lead to a marked reduction in size of rheumatoid nodules in RA patients. More studies are necessary to confirm whether this is an RTX-specific effect.
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