ArticleVirchows Archiv : an international journal of pathology2012
Serrated polyps of the colon: how reproducible is their classification?
Article in Virchows Archiv : an international journal of pathology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer.The American journal of gastroenterology · 2020Guideline
- British Society of Gastroenterology position statement on serrated polyps in the colon and rectum.Gut · 2017Guideline
- Histopathological and Molecular Features of Adenomatous and Serrated Colon Adenomas, Characteristics and Overlapping Features, Challenges in the Nomenclature.Turk patoloji dergisi · 2026Article
- Prevalence, risk factors, and BRAF mutation of colorectal sessile serrated lesions among Vietnamese patients.World journal of clinical oncology · 2024Article
- Three pathologic criteria for reproducible diagnosis of colonic sessile serrated lesion versus hyperplastic polyp.Human pathology · 2023Article
- Korean Guidelines for Postpolypectomy Colonoscopic Surveillance: 2022 revised edition.Intestinal research · 2023Review
- Korean guidelines for postpolypectomy colonoscopic surveillance: 2022 revised edition.Clinical endoscopy · 2022Review
- [Korean Guidelines for Postpolypectomy Colonoscopic Surveillance: 2022 Revised Edition].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2022Review
- Gastric metaplasia could initiate the serrated neoplasia pathway in CRC.Nature reviews. Gastroenterology & hepatology · 2022Article
- Clinicopathological Correlates of Dysplastic Sessile Serrated Lesion: A Prospective Cohort Study With a High Detection Rate.Gastro hep advances · 2022Article
- Interobserver agreement and the impact of mentorship on the diagnosis of inflammatory bowel disease-associated dysplasia among subspecialist gastrointestinal pathologists.Virchows Archiv : an international journal of pathology · 2021Article
- The Genomic Landscape of Serrated Lesion of the Colorectum: Similarities and Differences With Tubular and Tubulovillous Adenomas.Frontiers in oncology · 2021Article
- Hyperplastic polyp or sessile serrated lesion? The contribution of serial sections to reclassification.Diagnostic pathology · 2020Article
- Gastric and small intestinal traditional serrated adenomas: a detailed morphologic and immunohistochemical analysis.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2020Article
- Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer.Gastroenterology · 2020Article
- Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer.Gastrointestinal endoscopy · 2020Article
- Traditional serrated adenoma: an overview of pathology and emphasis on molecular pathogenesis.BMJ open gastroenterology · 2019Review
- Management of Serrated Polyps of the Colon.Current treatment options in gastroenterology · 2018Review
- Herniation of crypts in hyperplastic polyp and sessile serrated adenoma: a prospective study.American journal of cancer research · 2018Article
- Active BRAF-V600E is the key player in generation of a sessile serrated polyp-specific DNA methylation profile.PloS one · 2018Article
Corrections and comments
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Authors and funding
21 authors.
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Abstract
For several years, the lack of consensus on definition, nomenclature, natural history, and biology of serrated polyps (SPs) of the colon has created considerable confusion among pathologists. According to the latest WHO classification, the family of SPs comprises hyperplastic polyps (HPs), sessile serrated adenomas/polyps (SSA/Ps), and traditional serrated adenomas (TSAs). The term SSA/P with dysplasia has replaced the category of mixed hyperplastic/adenomatous polyps (MPs). The present study aimed to evaluate the reproducibility of the diagnosis of SPs based on currently available diagnostic criteria and interactive consensus development. In an initial round, H&E slides of 70 cases of SPs were circulated among participating pathologists across Europe. This round was followed by a consensus discussion on diagnostic criteria. A second round was performed on the same 70 cases using the revised criteria and definitions according to the recent WHO classification. Data were evaluated for inter-observer agreement using Kappa statistics. In the initial round, for the total of 70 cases, a fair overall kappa value of 0.318 was reached, while in the second round overall kappa value improved to moderate (kappa = 0.557; p < 0.001). Overall kappa values for each diagnostic category also significantly improved in the final round, reaching 0.977 for HP, 0.912 for SSA/P, and 0.845 for TSA (p < 0.001). The diagnostic reproducibility of SPs improves when strictly defined, standardized diagnostic criteria adopted by consensus are applied.
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