ArticleGenome research2013
Genome-wide patterns of natural variation reveal strong selective sweeps and ongoing genomic conflict in Drosophila mauritiana.
Article in Genome research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed.
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- Hybrid Sterility, Genetic Conflict and Complex Speciation: Lessons From theFrontiers in genetics · 2021Review
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- piRNA silencing contributes to interspecies hybrid sterility and reproductive isolation in Drosophila melanogaster.Nucleic acids research · 2019Article
- Evolution of salivary glue genes in Drosophila species.BMC evolutionary biology · 2019Article
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- Evolution of maternal and zygotic mRNA complements in the early Drosophila embryo.PLoS genetics · 2018Article
- Highly Contiguous Genome Assemblies of 15G3 (Bethesda, Md.) · 2018Article
- Dense infraspecific sampling reveals rapid and independent trajectories of plastome degradation in a heterotrophic orchid complex.The New phytologist · 2018Article
- High rate of translocation-based gene birth on theProceedings of the National Academy of Sciences of the United States of America · 2017Article
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- Molecular Population Genetics.Genetics · 2017Review
- Population structure and local selection yield high genomic variation in Mimulus guttatus.Molecular ecology · 2017Article
- Chromosomal inversions and ecotypic differentiation in Anopheles gambiae: the perspective from whole-genome sequencing.Molecular ecology · 2016Article
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4 authors.
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Abstract
Although it is well understood that selection shapes the polymorphism pattern in Drosophila, signatures of classic selective sweeps are scarce. Here, we focus on Drosophila mauritiana, an island endemic, which is closely related to Drosophila melanogaster. Based on a new, annotated genome sequence, we characterized the genome-wide polymorphism by sequencing pooled individuals (Pool-seq). We show that the interplay between selection and recombination results in a genome-wide polymorphism pattern characteristic for D. mauritiana. Two large genomic regions (>500 kb) showed the signature of almost complete selective sweeps. We propose that the absence of population structure and limited geographic distribution could explain why such pronounced sweep patterns are restricted to D. mauritiana. Further evidence for strong adaptive evolution was detected for several nucleoporin genes, some of which were not previously identified as genes involved in genomic conflict. Since this adaptive evolution is continuing after the split of D. mauritiana and Drosophila simulans, we conclude that genomic conflict is not restricted to short episodes, but rather an ongoing process in Drosophila.
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