Evidence map›Paper›PMID 23051607›Full record

ReviewBiochimica et biophysica acta2013

Phospholipids: "greasing the wheels" of humoral immunity.

Joseph W Brewer

Abstract readReview
In one paragraph

Review in Biochimica et biophysica acta, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Magnitude of obesity alone does not alter the alveolar lipidome.American journal of physiology. Lung cellular and molecular physiology · 2024
    Article
  2. The lipidome of posttraumatic stress disorder.bioRxiv : the preprint server for biology · 2024
    Article
  3. Observational
  4. TTC7A: Steward of Intestinal Health.Cellular and molecular gastroenterology and hepatology · 2019
    Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Joseph W BrewerDepartment of Microbiology and Immunology, College of Medicine, University of South Alabama, 5851 USA Drive North Mobile, AL 36688, USA. jbrewer@southalabama.edu
University of South Alabama · US

Funding

HOMEOSTASIS OF THE ER IN DIFFERENTIATING B CELLSR01GM061970 · NIGMS · UNIVERSITY OF SOUTH ALABAMA · PI BARRINGTON, ROBERT A · 2000 to 2013
$3.5M
NIGMS NIH HHS GM061970NIGMS NIH HHS R01 GM061970
6 · The paper itself

Abstract

Phospholipids are major structural components of all cellular membranes. In addition, certain phospholipids execute regulatory activities that affect cell behavior, function and fate in critically important physiological settings. The influence of phospholipids is especially obvious in the adaptive immune system, where these macromolecules mediate both intrinsic and extrinsic effects on B and T lymphocytes. This review article highlights the action of lysophospholipid sphingosine-1-phosphate as a lymphocyte chemoattractant, the function of phosphatidylinositol phosphates as signaling conduits in lymphocytes and the role of phospholipids as raw materials for membrane assembly and organelle biogenesis in activated B lymphocytes. Special emphasis is placed on the means by which these three processes push humoral immune responses forward. This article is part of a Special Issue entitled Phospholipids and Phospholipid Metabolism.

Indexed as

Immunity, HumoralAnimalsB-LymphocytesCell DifferentiationCell MembraneCell ProliferationChemotaxisHumansLymphocyte ActivationLysophospholipidsMiceSignal TransductionSphingosineT-Lymphocyteslysophosphatidic acidLysophospholipidsSphingosinesphingosine 1-phosphate

Identifiers

PMID23051607
PMCPMC3562403
OpenAlexW2007824269

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.