Evidence map›Paper›PMID 23050967›Full record

ReviewAnnals of the New York Academy of Sciences2012

Cutaneous responses to environmental stressors.

Giuseppe Valacchi, Claudia Sticozzi, Alessandra Pecorelli, Franco Cervellati, Carlo Cervellati, Emanuela Maioli

Open access · bronzeAbstract readReview
In one paragraph

Review in Annals of the New York Academy of Sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 1 pooled it
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 1 synthesis or guideline pooled it, 231 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. All-Flex Plasma Patch for In Vivo Delivery of Reactive Species.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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  9. Long-Term PMLife (Basel, Switzerland) · 2025
    Review
  10. TotalInternational journal of molecular sciences · 2025
    Article
  11. Article
  12. Article
  13. Unveiling the Skin Anti-Aging Potential of the NovelInternational journal of molecular sciences · 2025
    Article
  14. Review
  15. Article
  16. Article
  17. Air Pollution and Skin Diseases.Annals of dermatology · 2025
    Review
  18. Article
  19. Article
  20. Reversing Glycation with a Dietary Supplement Containing Rosemary Extract.The Journal of clinical and aesthetic dermatology · 2025
    Review

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Giuseppe ValacchiDepartment of Evolutionary Biology, University of Ferrara, Ferrara, Italy. giuseppe.valacchi@unife.it
Claudia Sticozzi
Alessandra Pecorelli
Franco Cervellati
Carlo Cervellati
Emanuela Maioli
University of Ferrara · ITUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Living organisms are continuously exposed to environmental pollutants. Because of its critical location, the skin is a major interface between the body and the environment and provides a biological barrier against an array of chemical and physical environmental pollutants. The skin can be defined as our first defense against the environment because of its constant exposure to oxidants, including ultraviolet (UV) radiation and other environmental pollutants such as diesel fuel exhaust, cigarette smoke (CS), halogenated hydrocarbons, heavy metals, and ozone (O₃). The exposure to environmental pro-oxidant agents leads to the formation of reactive oxygen species (ROS) and the generation of bioactive molecules that can damage skin cells. This short review provides an overview of the effects and mechanisms of action of CS, O₃, and UV on cutanous tissues.

Indexed as

AgingAdministration, CutaneousAir PollutantsAldehydesAnimalsCarbon Compounds, InorganicEnvironmental ExposureEnvironmental PollutantsHumansOzoneSkinSulfidesTobacco Smoke PollutionUltraviolet RaysAir PollutantsAldehydesCarbon Compounds, Inorganiccarbon sulfideEnvironmental PollutantsOzoneSulfidesTobacco Smoke Pollution

Identifiers

PMID23050967
PMCPMC3495295
OpenAlexW1641771942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.