ArticleCardiology research and practice2012
The continuing challenges of translational research: clinician-scientists' perspective.
Article in Cardiology research and practice, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Platelet-derived biomaterials in osteoporosis: mechanisms, evidence and translational prospects.Journal of biological engineering · 2026Review
- Embracing complexity: An opportunity for developmental evaluation.Journal of clinical and translational science · 2026Article
- Targeting tumor immune evasion: the role of PD-L1 siRNA in advancing cancer immunotherapy.Medical oncology (Northwood, London, England) · 2025Review
- Advancing research translation in addiction and pain: A portfolio analysis of the NIH HEAL initiative.Journal of clinical and translational science · 2025Article
- Translational research in psychiatry.Industrial psychiatry journal · 2024Article
- Using the Homeland Security Exercise and Evaluation Program (HSEEP) Building Block Approach to Implement System Evaluation Theory (SET).The American journal of evaluation · 2021Article
- A 30-year analysis of National Institutes of Health-funded cardiac transplantation research: Surgeons lead the way.The Journal of thoracic and cardiovascular surgery · 2021Article
- Options for Meaningful Engagement in Clinical Research for Busy Frontline Clinicians.Journal of general internal medicine · 2021Article
- Translational research in biomedical sciences in India: Challenges, observations & national perspectives.The Indian journal of medical research · 2020Article
- Best practices for enhancing surgical research: a perspective from the Canadian Association of Chairs of Surgical ResearchCanadian journal of surgery. Journal canadien de chirurgie · 2019Article
- A Roadmap for Aspiring Surgeon-Scientists in Today's Healthcare Environment.Annals of surgery · 2019Review
- Intervening to enhance collaboration in translational research: A relational coordination approach.Journal of clinical and translational science · 2017Article
- Evaluation of the informatician perspective: determining types of research papers preferred by clinicians.BMC medical informatics and decision making · 2017Article
- The Future of Basic Science in Academic Surgery: Identifying Barriers to Success for Surgeon-scientists.Annals of surgery · 2017Article
- A logic model for community engagement within the Clinical and Translational Science Awards consortium: can we measure what we model?Academic medicine : journal of the Association of American Medical Colleges · 2013Article
- Translational physiology: from molecules to public health.The Journal of physiology · 2013Review
- Implementation science: from evidence to practice.Acta medica colombiana : AMC : organo de la Asociacion Columbiana de Medicina InternaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the last twenty years, revolutionary advances in biomedicine including gene therapy, stem cell research, proteomics, genomics and nanotechnology have highlighted the progressive need to restructure traditional approaches to basic and clinical research in order to facilitate the rapid, efficient integration and translation of these new technologies into novel effective therapeutics. Over the past ten years, funding bodies in the USA and UK such as the National Institutes of Health (NIH) and the Medical Research Council (MRC) have been driving translational research by defining and tackling the hurdles but more still remains to be achieved. This article discusses the ongoing challenges translational researchers face and outlines recent initiatives to tackle these including the new changes to translational funding schemes proposed by the NIH and the MRC and the launch of the "European Advanced Translational Research InfraStructure in Medicine" (EATRIS). It is anticipated that initiatives such as these will not only strengthen translational biomedical research programmes already initiated but should lead to rapid benefits to patients and society.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.