ArticleISRN oncology2012
Looking in the mouth for noninvasive gene expression-based methods to detect oral, oropharyngeal, and systemic cancer.
Article in ISRN oncology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Comparing Two Methods for the Isolation of Exosomes.Journal of nucleic acids · 2022Article
- Analysis of primary oral and oropharyngeal squamous cell carcinoma in inhabitants of Beijing, China-a 10-year continuous single-center study.BMC oral health · 2020Article
- A loss of profilin-1 in late-stage oral squamous cell carcinoma.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2017Article
- Improving accuracy of RNA-based diagnosis and prognosis of oral cancer by using noninvasive methods.Oral oncology · 2017Review
- Salivary MMP-9 in the detection of oral squamous cell carcinoma.Medicina oral, patologia oral y cirugia bucal · 2017Article
- microRNA from brush biopsy to characterize oral squamous cell carcinoma epithelium.Cancer medicine · 2017Article
- Oral cancer incidence and mortality in China, 2011.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2015Article
- miR-98 suppresses tumor cell growth and metastasis by targeting IGF1R in oral squamous cell carcinoma.International journal of clinical and experimental pathology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Noninvasive diagnosis, whether by sampling body fluids, body scans, or other technique, has the potential to simplify early cancer detection. A classic example is Pap smear screening, which has helped to reduce cervical cancer 75% over the last 50 years. No test is error-free; the real concern is sufficient accuracy combined with ease of use. This paper will discuss methods that measure gene expression or epigenetic markers in oral cells or saliva to diagnose oral and pharyngeal cancers, without requiring surgical biopsy. Evidence for lung and other distal cancer detection is also reviewed.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.