ArticleInterface focus2011
Biomimetic three-dimensional microenvironment for controlling stem cell fate.
Article in Interface focus, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Review
- The regenerative journey: exploring stem cell roles from injury detection to tissue repair.Stem cell research & therapy · 2025Review
- Synergistic potential of stem cells and microfluidics in regenerative medicine.Molecular and cellular biochemistry · 2025Review
- 3D printing of bio-instructive materials: Toward directing the cell.Bioactive materials · 2023Article
- Droplet microfluidic devices for organized stem cell differentiation into germ cells: capabilities and challenges.Biophysical reviews · 2021Review
- A Substrate-Mimicking Basement Membrane Drives the Organization of Human Mesenchymal Stromal Cells and Endothelial Cells Into Perivascular Niche-Like Structures.Frontiers in cell and developmental biology · 2021Article
- Regulation of endothelial cell arrangements within hMSC - HUVEC co-cultured aggregates.Biomedical journal · 2019Article
- Biomimetic human lung-on-a-chip for modeling disease investigation.Biomicrofluidics · 2019Review
- Osteoarthritic human chondrocytes proliferate in 3D co-culture with mesenchymal stem cells in suspension bioreactors.Journal of tissue engineering and regenerative medicine · 2018Article
- Remodeling the Human Adult Stem Cell Niche for Regenerative Medicine Applications.Stem cells international · 2017Review
- Bioresponsive Hydrogels: Chemical Strategies and Perspectives in Tissue Engineering.Gels (Basel, Switzerland) · 2016Review
- A Method of Three-Dimensional Micro-Rotational Flow Generation for Biological Applications.Micromachines · 2016Article
- Regeneration of a Compromized Masticatory Unit in a Large Mandibular Defect Caused by a Huge Solitary Bone Cyst: A Case Report and Review of the Regenerative Literature.Journal of maxillofacial and oral surgery · 2016Article
- Opportunities and challenges in three-dimensional brown adipogenesis of stem cells.Biotechnology advances · 2015Review
- Precision assembly of complex cellular microenvironments using holographic optical tweezers.Scientific reports · 2015Article
- Physical, Spatial, and Molecular Aspects of Extracellular Matrix of In Vivo Niches and Artificial Scaffolds Relevant to Stem Cells Research.Stem cells international · 2015Review
- Extracellular matrix: a dynamic microenvironment for stem cell niche.Biochimica et biophysica acta · 2014Review
- Influence of the microenvironment on cell fate determination and migration.Physiological genomics · 2014Review
- Controlling self-renewal and differentiation of stem cells via mechanical cues.Journal of biomedicine & biotechnology · 2012Review
- Gene expression of single human mesenchymal stem cell in response to fluid shear.Journal of tissue engineering · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stem cell therapy is an emerging technique which is being translated into treatment of degenerated tissues. However, the success of translation relies on the stem cell lineage commitment in the degenerated regions of interest. This commitment is precisely controlled by the stem cell microenvironment. Engineering a biomimetic three-dimensional microenvironment enables a thorough understanding of the mechanisms of governing stem cell fate. We review the individual microenvironment components, including soluble factors, extracellular matrix, cell-cell interaction and mechanical stimulation. The perspectives in creating the biomimetic microenvironments are discussed with emerging techniques.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.