ArticleCurrent cardiovascular risk reports2012
Cognition and Hemodynamics.
Article in Current cardiovascular risk reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Magnetic resonance imaging for assessment of cerebrovascular reactivity and its relationship to cognition: a systematic review.BMC neuroscience · 2018Pooled it
- Review
- Cerebral Haemodynamics and Cognitive Impairment in Chronic Haemodialysis Patients: A Pilot Study.Journal of clinical medicine · 2025Article
- Risk Factors, Pathological Changes, and Potential Treatment of Diabetes-Associated Cognitive Dysfunction.Journal of diabetes · 2025Review
- The influence of cardiovascular fitness and ventilatory efficiency on fMRI assessed cerebrovascular reactivity in older adults.Frontiers in physiology · 2025Article
- Neurobiological Mechanisms of Cognitive Decline Correlated with Brain Aging.Advances in experimental medicine and biology · 2023Article
- Cerebrovascular Function, Vascular Risk, and Lifestyle Patterns in Resistant Hypertension.Journal of Alzheimer's disease : JAD · 2022Article
- Age-related changes in cerebrovascular health and their effects on neural function and cognition: A comprehensive review.Psychophysiology · 2021Review
- Sex moderations in the relationship between aortic stiffness, cognition, and cerebrovascular reactivity in healthy older adults.PloS one · 2021Article
- Association of HIV serostatus and metabolic syndrome with neurobehavioral disturbances.Journal of neurovirology · 2020Article
- Hemodynamic latency is associated with reduced intelligence across the lifespan: an fMRI DCM study of aging, cerebrovascular integrity, and cognitive ability.Brain structure & function · 2020Article
- Small vessel disease to subcortical dementia: a dynamic model, which interfaces aging, cholinergic dysregulation and the neurovascular unit.Vascular health and risk management · 2019Review
- Investigating structural and perfusion deficits due to repeated head trauma in active professional fighters.NeuroImage. Clinical · 2018Article
- Regional Cerebrovascular Reactivity and Cognitive Performance in Healthy Aging.Journal of experimental neuroscience · 2018Article
- Vascular risk factors, cerebrovascular reactivity, and the default-mode brain network.NeuroImage · 2015Article
- Bidirectional interactions between neuronal and hemodynamic responses to transcranial direct current stimulation (tDCS): challenges for brain-state dependent tDCS.Frontiers in systems neuroscience · 2015Article
- Executive functioning and the metabolic syndrome: a project FRONTIER study.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The relationship between cerebral hemodynamics and cognitive performance has increasingly become recognized as a major challenge in clinical practice for older adults. Both diabetes and hypertension worsen brain perfusion and are major risk factors for cerebrovascular disease, stroke and dementia. Cerebrovascular reserve has emerged as a potential biomarker for monitoring pressure-perfusion-cognition relationships. Endothelial dysfunction and inflammation, microvascular disease, and mascrovascular disease affect cerebral hemodynamics and play an important role in pathohysiology and severity of multiple medical conditions, presenting as cognitive decline in the old age. Therefore, the identification of cerebrovascular vascular reactivity as a new therapeutic target is needed for prevention of cognitive decline late in life.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.