ArticlePloS one2012
Living with cat and dog increases vaginal colonization with E. coli in pregnant women.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 70 citations in OpenAlex.
- Society and the Microbiome: A Biopsychosocial Window Into Comprehensive Well-Being: A Review.Health science reports · 2026Article
- Microbial Interconnections in One Health: A Critical Nexus Between Companion Animals and Human Microbiomes.Microorganisms · 2025Review
- Vaginal colonization, vertical transmission rate, antimicrobial susceptibility profile, and associated factors of potential neonatal pathogens among pregnant women at public health facilities of Northeast Ethiopia.Frontiers in public health · 2025Article
- Association between Pet Ownership and Threatened Abortion in Pregnant Women: The China Birth Cohort Study.International journal of environmental research and public health · 2022Article
- Article
- Season of Birth Impacts the Neonatal Nasopharyngeal Microbiota.Children (Basel, Switzerland) · 2020Article
- Dynamic changes of gut and lung microorganisms during chronic obstructive pulmonary disease exacerbations.The Kaohsiung journal of medical sciences · 2020Article
- Amplicon sequencing provides more accurate microbiome information in healthy children compared to culturing.Communications biology · 2019Article
- Rectovaginal Colonization With PathogenicInfection and drug resistance · 2019Article
- Exposure to household furry pets influences the gut microbiota of infant at 3-4 months following various birth scenarios.Microbiome · 2017Article
- Antimicrobial resistance trends among canine Escherichia coli isolates obtained from clinical samples in the northeastern USA, 2004-2011.The Canadian veterinary journal = La revue veterinaire canadienne · 2015Article
- Combined effects of prenatal medication use and delivery type are associated with eczema at age 2 years.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2015Article
- The murine lung microbiome in relation to the intestinal and vaginal bacterial communities.BMC microbiology · 2013Article
- Infant gut microbiota and the hygiene hypothesis of allergic disease: impact of household pets and siblings on microbiota composition and diversity.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2013Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFurred pets in the household are known reservoirs for pathogenic bacteria, but it is not known if transmission of bacteria between pet and owner leads to significantly increased rate of infections. We studied whether cats and dogs living in the household of pregnant women affect the commensal vaginal flora, and furthermore the need for oral antibiotics and rate of urinary tract infections during pregnancy.
methodsThe novel unselected Copenhagen Prospective Study on Asthma in Childhood (COPSAC(2010)) pregnancy cohort of 709 women participated in this analysis. Detailed information on pet exposure, oral antibiotic prescriptions filled at pharmacy and urinary tract infection during pregnancy was obtained and verified prospectively during clinic visits. Vaginal cultures were obtained at pregnancy week 36.
resultsWomen, who had cat or dog in the home during pregnancy, had a different vaginal flora, in particular with increased Escherichia coli (E. coli) colonization; odds ratio after adjustment for lifestyle confounders and antibiotics 2.20, 95% CI, [1.27-3.80], p=0.005. 43% of women living with cat and/or dog in the home used oral antibiotics compared to 33% of women with no cat or dog; adjusted odds ratio 1.51, 95% CI, [1.08-2.12], p=0.016. Women living with cat had increased frequency of self-reported urinary tract infection; adjusted odds ratio 1.57, 95% CI, [1.02-2.43], p=0.042.
conclusionsThe increased vaginal E. coli colonization in women living with cat or dog suggests a clinically important transmission of pathogenic bacteria from pet to owner substantiated by increased rate of antibiotic use and urinary tract infections which, which is of particular concern during pregnancy.
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