ArticlePloS one2012
Association of left ventricular mass with all-cause mortality, myocardial infarction and stroke.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Effect of the geometry and severity of left ventricular hypertrophy on cardiovascular mortality in dialysis patients.Kidney research and clinical practice · 2026Article
- Increasing Left Ventricular Mass and Death in Men and Women Investigated With Echocardiography.Journal of the American Heart Association · 2025Article
- Heart volume on health checkup CT scans inversely correlates with pulse rate: data-driven analysis using deep-learning segmentation.Japanese journal of radiology · 2025Article
- Endothelial dysfunction influences augmented aortic hemodynamic responses to metaboreflex activation in postmenopausal women.European journal of applied physiology · 2024Article
- CoAt-Mixer: Self-attention deep learning framework for left ventricular hypertrophy using electrocardiography.PloS one · 2023Article
- CHA2DS2-VASc score, P-wave indexes, and echocardiographic parameters in sinus rhythm patients without valvular heart disease.Revista da Associacao Medica Brasileira (1992) · 2023Article
- Effect of metformin on left ventricular mass and functional parameters in non-diabetic patients: a meta-analysis of randomized clinical trials.BMC cardiovascular disorders · 2022Article
- Risk for subsequent hypertension and cardiovascular disease after living kidney donation: is it clinically relevant?Clinical kidney journal · 2022Review
- Relations Between Cardiac Magnetic Resonance Imaging-Derived Left Ventricular Mass, Early Repolarization, and Cardiovascular Events (from the Dallas Heart Study).The American journal of cardiology · 2021Article
- Prognostic Significance of Echocardiographic Measures of Cardiac Remodeling in the Community.Current cardiology reports · 2021Review
- Cardiovascular Effects of Unilateral Nephrectomy in Living Kidney Donors at 5 Years.Hypertension (Dallas, Tex. : 1979) · 2021Article
- Cardiovascular Imaging in Obesity.Nutrients · 2021Review
- The Role of Transthoracic Echocardiography in the Evaluation of Patients With Ischemic Stroke.Frontiers in cardiovascular medicine · 2021Article
- A Contemporary Approach to Hypertensive Cardiomyopathy: Reversing Left Ventricular Hypertrophy.Current hypertension reports · 2020Review
- Article
- QTc dispersion and Cornell duration product can predict 10-year outcomes in hypertensive patients with left ventricular hypertrophy.Clinical cardiology · 2017Article
- Cardiac remodeling and dysfunction in childhood obesity: a cardiovascular magnetic resonance study.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2016Article
- Article
- Association of serum leptin with future left ventricular structure and function: The Multi-Ethnic Study of Atherosclerosis (MESA).International journal of cardiology · 2015Article
- Echocardiography in hypertension: a call for standardization from the Working Group on Heart and Hypertension of the Italian Society of Hypertension.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2014Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOur aim was to assess the association of left ventricular mass with mortality and nonfatal cardiovascular events. METHODOLOGY/PRINCIPAL
findingsLeft ventricular mass was measured by echocardiography in 40138 adult patients (mean age 61.1 ± 16.4 years, 52.5% male). The primary endpoint was all-cause mortality. Secondary endpoints included nonfatal myocardial infarction and nonfatal stroke. During a mean follow-up period of 5.6 ± 3.9 years, 9181 patients died, 901 patients had a nonfatal myocardial infarction, and 2139 patients had a nonfatal stroke. Cumulative 10-year mortality was 26.8%, 31.9%, 37.4% and 46.4% in patients with normal, mildly, moderately and severely increased left ventricular mass, respectively (p<0.001). Ten-year rates of nonfatal myocardial infarction and stroke ranged from 3.2% and 6.7% in patients with normal left ventricular mass to 5.3% and 12.7% in those with severe increase in left ventricular mass, respectively. After multivariate adjustment, left ventricular mass remained an independent predictor of all-cause mortality (hazard ratio [HR] per 100 g increase 1.21, 95% confidence interval [CI] 1.14-1-27, p<0.001 in women, and HR 1.09, 95% CI 1.04-1-13, p<0.001 in men), myocardial infarction (HR 1.60, 95% CI 1.31-1.94, p<0.001 in women and HR 1.15, 95% CI 1.02-1.29, p=0.019 in men) and stroke (HR 1.26, 95% CI 1.13-1.40, p<0.001 in women and HR 1.19, 95% CI 1.09-1.30, p<0.001 in men). CONCLUSIONS/SIGNIFICANCE: Left ventricular mass has a graded and independent association with all-cause mortality, myocardial infarction and stroke.
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