ArticlePloS one2012
Factors influencing the estimates of correlation between motor unit activities in humans.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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Who cites it
51 citing papers in PubMed.
- Dual-Tasking Exacerbates Force and Neural Control Unsteadiness in Older Adults With Sarcopenia.Journal of cachexia, sarcopenia and muscle · 2026Article
- Sex differences in climbing endurance emerge from combined physiological adaptation and neural strategies.European journal of applied physiology · 2026Article
- Differential changes in the effective neural drive following new motor skill acquisition between vastus lateralis and medialis.European journal of applied physiology · 2026Article
- Online modulation of neural drive to lower motor neurons with high-definition transcranial alternating current stimulation (HD-tACS).Journal of neuroengineering and rehabilitation · 2026Article
- Modulation of Hamstrings Neural Drive During Isometric Contractions of the Hip Extensors and Knee Flexors.Scandinavian journal of medicine & science in sports · 2026Article
- Spinal motor neuron pools may be partly driven by impulsive common inputs.The Journal of physiology · 2026Article
- Article
- Blood flow restriction modulates common drive to motor units and force precision: implications for neuromuscular coordination.European journal of applied physiology · 2026Article
- A single low-dimensional neural component of spinal motor neuron activity explains force generation across repetitive isometric tasks.iScience · 2025Article
- Effects of Aging on Motor Unit Properties in Isometric Elbow Flexion.Bioengineering (Basel, Switzerland) · 2025Article
- Effects of Ankle Joint Angles and Surrounding Muscles on Hip Joint Musculature.Journal of functional morphology and kinesiology · 2025Article
- Higher dominant muscle strength is mediated by motor unit discharge rates and proportion of common synaptic inputs.Scientific reports · 2025Article
- Article
- Effects of blood flow restriction on motoneurons synchronization.Frontiers in neural circuits · 2025Article
- Changes in motor unit behaviour across repeated bouts of eccentric exercise.Experimental physiology · 2024Article
- Article
- The neural control of movement: a century of in vivo motor unit recordings is the legacy of Adrian and Bronk.The Journal of physiology · 2024Review
- Two motor neuron synergies, invariant across ankle joint angles, activate the triceps surae during plantarflexion.The Journal of physiology · 2023Article
- Common synaptic input, synergies and size principle: Control of spinal motor neurons for movement generation.The Journal of physiology · 2023Review
- A computational approach for generating continuous estimates of motor unit discharge rates and visualizing population discharge characteristics.Journal of neural engineering · 2022Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlpha motoneurons receive common synaptic inputs from spinal and supraspinal pathways. As a result, a certain degree of correlation can be observed between motoneuron spike trains during voluntary contractions. This has been studied by using correlation measures in the time and frequency domains. These measures are interpreted as reflecting different types of connectivity in the spinal networks, although the relation between the degree of correlation of the output motoneuron spike trains and of their synaptic inputs is unclear. METHODOLOGY/PRINCIPAL
findingsIn this study, we analyze theoretically this relation and we complete this analysis by simulations and experimental data on the abductor digiti minimi muscle. The results demonstrate that correlation measures between motoneuron output spike trains are inherently influenced by the discharge rate and that this influence cannot be compensated by normalization. Because of the influence of discharge rate, frequency domain measures of correlation (coherence) do not identify the full frequency content of the common input signal when computed from pairs of motoneurons. Rather, an increase in sampling rate is needed by using cumulative spike trains of several motoneurons. Moreover, the application of averaging filters to the spike trains influences the magnitude of the estimated correlation levels calculated in the time, but not in the frequency domain (coherence).
conclusionsIt is concluded that the analysis of coherence in different frequency bands between cumulative spike trains of a sufficient number of motoneurons provides information on the spectrum of the common synaptic input. Nonetheless, the absolute values of coherent peaks cannot be compared across conditions with different cumulative discharge rates.
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