ArticleFrontiers in endocrinology2012
Purinergic signalling in bone.
Article in Frontiers in endocrinology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Identification of hub genes and molecular networks involved in alveolar bone resorption based on bioinformatics analysis.Scientific reports · 2026Article
- ATP release mediated by pannexin-3 is required for plasma cell survival via P2X4 receptors in bone marrow.Purinergic signalling · 2025Article
- Effect of antiplatelet and anticoagulant medications on implant survival: a long-term retrospective cohort study.Oral and maxillofacial surgery · 2025Article
- Extracellular adenosine signaling in bone health and disease.Current opinion in pharmacology · 2023Review
- Activation of GDNF-ERK-Runx1 signaling contributes to P2X3R gene transcription and bone cancer pain.iScience · 2022Article
- Absence of P2YFrontiers in endocrinology · 2022Article
- The P2RX7B splice variant modulates osteosarcoma cell behaviour and metastatic properties.Journal of bone oncology · 2021Article
- Review
- Article
- Methylosome protein 50 associates with the purinergic receptor P2X5 and is involved in osteoclast maturation.FEBS letters · 2020Article
- Effect of clopidogrel in bone healing-experimental study in rabbits.World journal of orthopedics · 2019Article
- Tissue engineered bone mimetics to study bone disorders ex vivo: Role of bioinspired materials.Biomaterials · 2019Review
- Signaling of the Purinergic System in the Joint.Frontiers in pharmacology · 2019Review
- Article
- Updating osteoimmunology: regulation of bone cells by innate and adaptive immunity.Nature reviews. Rheumatology · 2018Review
- The purinergic receptor P2X5 regulates inflammasome activity and hyper-multinucleation of murine osteoclasts.Scientific reports · 2017Article
- Extracellular ATP and other nucleotides-ubiquitous triggers of intercellular messenger release.Purinergic signalling · 2016Review
- Review
- Correlation between P2X7 receptor gene polymorphisms and gout.Rheumatology international · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Purinergic signaling in bone was first proposed in the early 1990s with the observation that extracellular ATP could modulate events crucial to the normal functioning of bone cells. Since then the expression of nearly all the P2Y and P2X receptors by osteoblasts and osteoclasts has been reported, mediating multiple processes including cell proliferation, differentiation, function, and death. This review will highlight the most recent developments in the field of purinergic signaling in bone, with a special emphasis on recent work resulting from the European Framework 7 funded collaboration ATPBone, as well as Arthritis Research UK and Bone Research Society supported projects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.