Evidence map›Paper›PMID 23049471›Full record

ArticlePoint of care2012

Assessing Point-of-Care Device Specifications and Needs for Pathogen Detection in Emergencies and Disasters.

Gerald J Kost, Daniel M Mecozzi, T Keith Brock, Corbin M Curtis

Abstract read
In one paragraph

Article in Point of care, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Molecular diagnosis of sepsis: New aspects and recent developments.European journal of microbiology & immunology · 2014
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Gerald J KostUC Davis-LLNL Center for Point-of-Care Technologies [NIBIB, NIH]; Point-of-Care Testing for Teaching and Research [POCT•CTR]; Pathology and Laboratory Medicine, School of Medicine, University of California, Davis, California, USA 95616.
Daniel M Mecozzi
T Keith Brock
Corbin M Curtis
University of California, Davis · US

Funding

Rapid Multipathogen Detection for POCT and National Diaster ReadinessU54EB007959 · NIBIB · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KOST, GERALD JOSEPH · 2007 to 2011
$8.5M
NIBIB NIH HHS U54 EB007959
6 · The paper itself

Abstract

backgroundWe assessed point-of-care device specifications and needs for pathogen detection in urgent care, emergencies, and disasters.

methodsWe surveyed American Association for Clinical Chemistry members and compared responses to those of disaster experts. Online SurveyMonkey questions covered performance characteristics, device design, pathogen targets, and other specifications.

resultsFor disasters, respondents preferred direct sample collection with a disposable test cassette that stores biohazardous material (P<0.001). They identified methicillin-resistant Staphylococcus aureus, Salmonella typhi, Vibrio cholerae, Escherichia coli, Staphylococcus aureus, and Streptococcus pneumoniae as high priority pathogens. First responders were deemed the professional group who should perform POC testing in disasters (P<0.001).

conclusionsNeeds assessment now is requisite for competitive funding, so the results in this report will be useful to investigators preparing grant applications. Point-of-care devices used in disasters should address the needs of first responders, who give high priority to contamination-free whole-blood sampling, superior performance pathogen detection, and HIV-1/2 blood donor screening. There was surprising concordance of preferences among different professional groups, which presages formulation of global consensus guidelines to assist high impact preparedness.

Identifiers

PMID23049471
PMCPMC3462026
OpenAlexW2009568575

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.