ArticleRevista brasileira de hematologia e hemoterapia2011
Titers of ABO antibodies in group O blood donors.
Article in Revista brasileira de hematologia e hemoterapia, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 49 citations in OpenAlex.
- Analysis of Titers of Immunoglobulin M and Immunoglobulin G ABO Antibodies in Group O Blood and Plateletphersis Donors at a Tertiary Care Hospital.Annals of African medicine · 2026Article
- Revisiting whole blood transfusion for the massively bleeding patient: The origins of resistance to change.Transfusion · 2026Article
- Article
- Prevalence of High Titre Anti-A and Anti-B Haemolysins Amongst Blood Group "O" Voluntary Donors at Mbale Regional Blood Bank, Eastern Uganda.Journal of blood medicine · 2025Article
- In-vitro Dilution of Human Plasma to Reduce ABO Antibody Titer Levels While Preserving Coagulation Factors.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2025Article
- Association Between Blood Groups and COVID-19 CT Severity: A Retrospective Analysis From a Tertiary Care Center.Cureus · 2023Article
- Characteristics of ABO Antibodies in Group O Malaysian Blood Donors.The Malaysian journal of medical sciences : MJMS · 2023Article
- COVID-19 host genetics and ABO blood group susceptibility.Cambridge prisms. Precision medicine · 2023Review
- ABO blood group and COVID-19: a review on behalf of the ISBT COVID-19 Working Group.Vox sanguinis · 2021Review
- Efficacy of convalescent plasma according to blood groups in COVID-19 patientsTurkish journal of medical sciences · 2021Article
- The potential use of ABO blood group system for risk stratification of COVID-19.Medical hypotheses · 2020Article
- Convalescent Plasma Therapy for COVID-19: State of the Art.Clinical microbiology reviews · 2020Review
- Blood type and the microbiome- untangling a complex relationship with lessons from pathogens.Current opinion in microbiology · 2020Review
- Quality improvement with platelet additive solution for safer out-of-group platelet transfusions.Immunohematology · 2019Article
- Titers of ABO antibodies in group O blood donors: patient safety and blood product supply remain a challenge.Revista brasileira de hematologia e hemoterapia · 2011Article
- ABO isoagglutinin titers in group "O" blood donors.Asian journal of transfusion scienceArticle
- Evaluation of immunoglobulin M and immunoglobulin G titers of ABO blood group system in blood donors at a blood center of a tertiary care hospital.Asian journal of transfusion scienceArticle
- Hemolysis in reverse grouping: Evaluation and implication of high titer isoagglutinin of two blood donors.Asian journal of transfusion scienceArticle
- Antibody titers in Group O platelet donors.Asian journal of transfusion scienceArticle
- Dangerous universal donors: the reality of the Hemocentro in Belo Horizonte, Minas Gerais.Revista brasileira de hematologia e hemoterapiaArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPlasma components of group O blood donations are rarely submitted to ABO antibody titrations even though it is well known that passively acquired antibodies may destroy the recipient's own red cells and tissue grafts.
objectiveThus, group O donations stratified by gender and age were randomly titrated to identify the best source of products for apheresis and exsanguinous transfusion.
methodsSamples from 603 blood donors were tested by ABO antibody titration using the conventional tube technique at room temperature. ABO antibody levels higher than 64 were considered high. After correction for gender, statistical analyses were performed using the Fisher exact and Kruskal-Wallis tests.
resultsMost donors in the blood bank were male (65.7%). ABO antibody titers ranged from 1 to 2048. The estimations of prevalence for the titers were: anti-A,B < 128 = 86.9% and = 128 = 2.16%; Anti-A = 128 = 9.29% and anti-B = 128 = 4.81%. Low mean titers for both anti-A and anti-B antibodies were found in over 50-year-old men (p-value = 0.040). High anti-B antibody levels were found in young women (p-value = 0.002).
conclusionThis study confirms that over 50-year-old O group men should be selected as blood donors in non-identical ABO transfusion situations. Also, titration of ABO antibodies in blood banks will increase safety in non-identical ABO transfusions.
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