Evidence map›Paper›PMID 23049260›Full record

ReviewVascular health and risk management2012

The prevention and regression of atherosclerotic plaques: emerging treatments.

Atul Ashok Kalanuria, Paul Nyquist, Geoffrey Ling

Abstract readReview
In one paragraph

Review in Vascular health and risk management, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Article
  3. Tuning macrophages for atherosclerosis treatment.Regenerative biomaterials · 2023
    Review
  4. Article
  5. Recombinant Destabilase fromCurrent issues in molecular biology · 2021
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Active matter therapeutics.Nano today · 2020
    Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Atul Ashok KalanuriaDivision of Neuro Critical Care, Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, USA.
Paul Nyquist
Geoffrey Ling

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Occlusive vascular diseases, such as sudden coronary syndromes, stroke, and peripheral arterial disease, are a huge burden on the health care systems of developed and developing countries. Tremendous advances have been made over the last few decades in the diagnosis and treatment of atherosclerotic diseases. Intravascular ultrasound has been able to provide detailed information of plaque anatomy and has been used in several studies to assess outcomes. The presence of atherosclerosis disrupts the normal protective mechanism provided by the endothelium and this mechanism has been implicated in the pathophysiology of coronary artery disease and stroke. Efforts are being put into the prevention of atherosclerosis, which has been shown to begin in childhood. This paper reviews the pathophysiology of atherosclerosis and discusses the current options available for the prevention and reversal of plaque formation.

Indexed as

AntioxidantsAtherosclerosisDiagnostic ImagingDietDisease ProgressionEpoprostenolEstrogensExerciseHumansHypolipidemic AgentsMass ScreeningNitrous OxidePlatelet Aggregation InhibitorsPrimary PreventionSecondary PreventionAntioxidantsEpoprostenolEstrogensHypolipidemic AgentsNitrous OxidePlatelet Aggregation Inhibitorsatherosclerotic diseasecardiovascularcoronary artery diseaseendotheliumplaquereversalstroke

Identifiers

PMID23049260
PMCPMC3459726

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.