ArticleMRS bulletin2012
Development of Electron Energy Loss Spectroscopy in the Biological Sciences.
Article in MRS bulletin, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 107 citations in OpenAlex.
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- Kinetically controlled hetero-fusion is a systems-level behaviour of polymer nanoparticle populations.Nature communications · 2025Article
- Cryogenic electron tomography and elemental analysis of mitochondrial granules in human retinal ganglion cells.Structure (London, England : 1993) · 2025Article
- Unifying frequency metrology across microwave, optical, and free-electron domains.Nature communications · 2025Article
- Low-Dose Elemental Mapping of Light Atoms in Liquid-phase Materials Using Cryo-EELS.Analytical chemistry · 2025Article
- Review
- Unravelling nonclassical beam damage mechanisms in metal-organic frameworks by low-dose electron microscopy.Nature communications · 2025Article
- Biochemical transformations of inorganic nanomedicines in buffers, cell cultures and organisms.Nanoscale · 2023Review
- Charting the molecular landscape of the cell.Structure (London, England : 1993) · 2023Review
- A spatially resolved elemental nanodomain organization within acidocalcisomes inProceedings of the National Academy of Sciences of the United States of America · 2023Article
- [Ultrastructure of pathologic deposits and cellular inclusions].Pathologie (Heidelberg, Germany) · 2023Review
- Electron tomography unravels new insights into fiber cell wall nanostructure; exploring 3D macromolecular biopolymeric nano-architecture of spruce fiber secondary walls.Scientific reports · 2023Article
- Combined Electron Microscopy Approaches for Arterial Glycocalyx Visualization.Frontiers in cardiovascular medicine · 2022Article
- Elemental mapping of labelled biological specimens at intermediate energy loss in an energy-filtered TEM acquired using a direct detection device.Journal of microscopy · 2021Article
- State-of-the-art microscopy to understand islets of Langerhans: what to expect next?Immunology and cell biology · 2021Review
- Tissue Specific Fate of Nanomaterials by Advanced Analytical Imaging Techniques - A Review.Chemical research in toxicology · 2020Review
- Time-resolved cathodoluminescence of DNA triggered by picosecond electron bunches.Scientific reports · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The high sensitivity of electron energy loss spectroscopy (EELS) for detecting light elements at the nanoscale makes it a valuable technique for application to biological systems. In particular, EELS provides quantitative information about elemental distributions within subcellular compartments, specific atoms bound to individual macromolecular assemblies, and the composition of bionanoparticles. The EELS data can be acquired either in the fixed beam energy-filtered transmission electron microscope (EFTEM) or in the scanning transmission electron microscope (STEM), and recent progress in the development of both approaches has greatly expanded the range of applications for EELS analysis. Near single atom sensitivity is now achievable for certain elements bound to isolated macromolecules, and it becomes possible to obtain three-dimensional compositional distributions from sectioned cells through EFTEM tomography.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.