Evidence map›Paper›PMID 23047780›Full record

ReviewMedical care2012

The state of disparities in opportunistic infection prophylaxis for blacks with HIV/AIDS.

Christine U Oramasionwu, Jim M Koeller, Kenneth A Lawson, Carolyn M Brown, Gene D Morse, Christopher R Frei

Open access · greenAbstract readReview
In one paragraph

Review in Medical care, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Christine U OramasionwuUNC Eshelman School of Pharmacy, Division of Pharmaceutical Outcomes and Policy, University of North Carolina at Chapel Hill, 2215 Kerr Hall, Chapel Hill, NC 27599-7573, USA. oramsc@unc.edu
Jim M Koeller
Kenneth A Lawson
Carolyn M Brown
Gene D Morse
Christopher R Frei
Austin College · USThe University of Texas at Austin · USUniversity at Buffalo, State University of New York · US

Funding

AIDS Clinical Trials Group NetworkU01AI068636 · NIAID · SOCIAL AND SCIENTIFIC SYSTEMS, INC. · PI KURITZKES, DANIEL R. · 2006 to 2010
$147.1M
Antiretroviral Pharmacology Training in Resource Poor CountriesD43TW007991 · FIC · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MORSE, GENE D. · 2009 to 2015
$1.6M
FIC NIH HHS D43TW007991-01A2NIAID NIH HHS U01AI068636NIMHD NIH HHS L60 MD003770
6 · The paper itself

Abstract

objectivesThe purpose of this review is to identify and analyze published studies that have evaluated disparities for opportunistic infection (OI) prophylaxis between blacks and whites with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) in the United States.

methodsThe authors conducted a web-based search of MEDLINE (1950-2009) to identify original research articles evaluating the use of OI prophylaxis between blacks and whites with HIV/AIDS. The search was conducted utilizing the following MeSH headings and search terms alone and in combination: HIV, AIDS, Black, race, ethnicity, disparities, differences, access, opportunistic infection, and prophylaxis. The search was then expanded to include any relevant articles from the referenced citations of the articles that were retrieved from the initial search strategy. Of the 29 articles retrieved from the literature search, 19 articles were excluded.

resultsTen publications met inclusion criteria, collectively published between 1991 and 2005. The collective time periods of these studies spanned from 1987 to 2001. Four studies identified a race-based disparity in that blacks were less likely than whites to use OI prophylaxis, whereas 5 studies failed to identify such a relationship between race and OI prophylaxis. One study identified disparities for Mycobacterium avium complex prophylaxis, but not for Pneumocystis jiroveci pneumonia prophylaxis.

conclusionsThe evidence regarding race-based disparities in OI prophylaxis is inconclusive. Additional research is warranted to explore potential race-based disparities in OI prophylaxis.

Indexed as

AIDS-Related Opportunistic InfectionsAntibiotic ProphylaxisBlack or African AmericanHealthcare DisparitiesHIV InfectionsHumansUnited StatesVaccination

Identifiers

PMID23047780
PMCPMC3470654
OpenAlexW1974697470

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.