ReviewNature reviews. Molecular cell biology2012
Advances in tomography: probing the molecular architecture of cells.
Review in Nature reviews. Molecular cell biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Accelerating electron tomography reconstruction algorithm ICON with GPU.Biophysics reports · 2017Article
- Toward correlating structure and mechanics of platelets.Cell adhesion & migration · 2016Review
- A new view into prokaryotic cell biology from electron cryotomography.Nature reviews. Microbiology · 2016Review
- Minicells, Back in Fashion.Journal of bacteriology · 2016Review
- Electron Tomography: A Three-Dimensional Analytic Tool for Hard and Soft Materials Research.Advanced materials (Deerfield Beach, Fla.) · 2015Review
- CT brush and CancerZap!: two video games for computed tomography dose minimization.Theoretical biology & medical modelling · 2015Article
- PCASSO: a fast and efficient Cα-based method for accurately assigning protein secondary structure elements.Journal of computational chemistry · 2014Article
- LipidWrapper: an algorithm for generating large-scale membrane models of arbitrary geometry.PLoS computational biology · 2014Article
- Broken nuclei--lamins, nuclear mechanics, and disease.Trends in cell biology · 2014Review
- Review
- From lamins to lamina: a structural perspective.Histochemistry and cell biology · 2013Review
- Unraveling the structure of viral replication complexes at super-resolution.Frontiers in plant science · 2013Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Visualizing the dynamic molecular architecture of cells is instrumental for answering fundamental questions in cellular and structural biology. Although modern microscopy techniques, including fluorescence and conventional electron microscopy, have allowed us to gain insights into the molecular organization of cells, they are limited in their ability to visualize multicomponent complexes in their native environment. Cryo-electron tomography (cryo-ET) allows cells, and the macromolecular assemblies contained within, to be reconstructed in situ, at a resolution of 2-6 nm. By combining cryo-ET with super-resolution fluorescence microscopy approaches, it should be possible to localize proteins with high precision inside cells and so elucidate a more realistic view of cellular processes. Thus, cryo-ET may bridge the resolution gap between cellular and structural biology.
Indexed as
Identifiers
23047735What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.