Evidence map›Paper›PMID 23046647›Full record

ReviewCurrent topics in membranes2012

Iron transport machinery of human cells: players and their interactions.

Ningning Zhao, Caroline A Enns

Abstract readReview
In one paragraph

Review in Current topics in membranes, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Of mitochondrion and COVID-19.Journal of enzyme inhibition and medicinal chemistry · 2021
    Review
  6. Review
  7. Ferrotoxicity and Its Amelioration by Calcitriol in Cultured Renal Cells.Analytical cellular pathology (Amsterdam) · 2021
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. VIPER is a genetically encoded peptide tag for fluorescence and electron microscopy.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  14. Ferroportin-Hepcidin Axis in Prepubertal Obese Children with Sufficient Daily Iron Intake.International journal of environmental research and public health · 2018
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ningning ZhaoDepartment of Cell and Developmental Biology, Oregon Health & Sciences University, Oregon, USA.
Caroline A Enns

Funding

The role of transferrin receptor 2 in iron homeostasisP01GM067166 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI UNGER, VINZENZ · 2003 to 2013
$14.6M
Function of the hemochromatosis proteinR37DK054488 · NIDDK · OREGON HEALTH & SCIENCE UNIVERSITY · PI ENNS, CAROLINE · 2010 to 2019
$4.0M
Regulation and function of transferrin receptor 2R01DK072166 · NIDDK · OREGON HEALTH & SCIENCE UNIVERSITY · PI ENNS, CAROLINE · 2005 to 2017
$3.7M
FUNCTION OF THE HEMOCHROMATOSIS PROTEINR01DK054488 · NIDDK · OREGON HEALTH & SCIENCE UNIVERSITY · PI ENNS, CAROLINE · 2000 to 2009
$3.1M
NIDDK NIH HHS DK054488NIDDK NIH HHS DK072166NIDDK NIH HHS R01 DK054488NIDDK NIH HHS R01 DK072166NIDDK NIH HHS R37 DK054488NIGMS NIH HHS P01 GM067166
6 · The paper itself

Abstract

Organisms, like cells, maintain tight control of iron. In humans as well as other mammals, control is achieved through the regulation of iron uptake into the body rather than through the excretion of iron. The mechanisms by which humans and mice regulate both iron uptake and the distribution of iron within the body and cells are reviewed. Special emphasis is given to the iron transporters involved in this process.

Indexed as

AnimalsBiological TransportCation Transport ProteinsHemeHumansIronReceptors, TransferrinTransferrinCation Transport ProteinsHemeIronReceptors, TransferrinTransferrin

Identifiers

PMID23046647
PMCPMC3934873

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.