Trial reportProceedings of the National Academy of Sciences of the United States of America2012
Effects of early intervention and the moderating effects of brain activity on institutionalized children's social skills at age 8.
Trial report in Proceedings of the National Academy of Sciences of the United States of America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 115 citations in OpenAlex.
- Electroencephalogram activity related to psychopathological and neuropsychological symptoms in institutionalised minors: a systematic review.Acta neuropsychiatrica · 2025Pooled it
- Effects of foster care intervention and caregiving quality on the bidirectional development of executive functions and social skills following institutional rearing.Developmental science · 2023Trial
- Early deprivation alters structural brain development from middle childhood to adolescence.Science advances · 2022Trial
- Long-Term Effects of Institutional Care and Enhanced Attachment Relationships on Close Adolescent Friendships.Child development · 2021Trial
- Improving social-emotional competence in internationally adopted children with the Attachment and Biobehavioral Catch-up intervention.Development and psychopathology · 2021Trial
- Long-term effects of institutional rearing, foster care, and brain activity on memory and executive functioning.Proceedings of the National Academy of Sciences of the United States of America · 2019Trial
- Early deprivation disruption of associative learning is a developmental pathway to depression and social problems.Nature communications · 2018Trial
- Effects of early institutionalization on the development of emotion processing: a case for relative sparing?Developmental science · 2015Trial
- Social communication difficulties and autism in previously institutionalized children.Journal of the American Academy of Child and Adolescent Psychiatry · 2015Trial
- Understanding everyday victimization experiences in vulnerable youth: an ecological momentary assessment approach.European child & adolescent psychiatry · 2026Article
- Shaping infants' social brains through vicarious social learning: the importance of positive mother-father interactions.Frontiers in psychology · 2024Article
- The impact of out-of-home care on brain development: a brief review of the neuroscientific evidence informing our understanding of children's attachment outcomes.Frontiers in behavioral neuroscience · 2024Review
- Timing of adoption is associated with electrophysiological brain activity and externalizing problems among children adopted internationally.Developmental psychobiology · 2022Article
- Growth in self-regulation over the course of adolescence mediates the effects of foster care on psychopathology in post-institutionalized children: a randomized clinical trial.Clinical psychological science : a journal of the Association for Psychological Science · 2021Article
- Friendship and social functioning following early institutional rearing: The role of ADHD symptoms.Development and psychopathology · 2019Article
- Moving Closer to Isolating Neurocognitive Mechanisms of Resilience to Anxiety in Youth With Early Childhood Adversity.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2019Article
- Signs of attachment disorders and social functioning among early adolescents with a history of institutional care.Child abuse & neglect · 2019Article
- How Early Experience Shapes Human Development: The Case of Psychosocial Deprivation.Neural plasticity · 2019Review
- Targeted Estimation of the Relationship Between Childhood Adversity and Fluid Intelligence in a US Population Sample of Adolescents.American journal of epidemiology · 2018Article
- Alternatives for abandoned children: insights from the Bucharest Early Intervention Project.Current opinion in psychology · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
The present study examined the social skills of previously institutionalized, 8-y-old Romanian children from the Bucharest Early Intervention Project and the influence of attachment security and brain electrical activity (alpha power) on these skills. Participants included children randomized to an intervention involving foster care [Foster Care Group (FCG)], children randomized to remain in institutions [Care As Usual Group (CAUG)], and never-institutionalized children living with their families in the Bucharest community [Never-Institutionalized Group (NIG)]. A continuous rating of children's attachment security to their primary caregiver was assessed at 42 mo of age. When children were 8 y old, teachers rated their social skills, and the children's resting electroencephalogram alpha power was recorded. Teachers rated social skills of FCG children who were placed into foster care before 20 mo of age as no different from NIG children, and both of these groups were higher than CAUG children and FCG children placed after 20 mo. Electroencephalogram alpha power at age 8 significantly moderated the relations between attachment security and social skills. These findings characterize institutionalized children's social skills in middle childhood within the context of a randomized intervention while highlighting the roles of both relational and biological factors in these developmental trajectories.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.