ArticleThe Journal of infectious diseases2012
Excess mortality associated with influenza A and B virus in Hong Kong, 1998-2009.
Article in The Journal of infectious diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 5 of them syntheses that pooled it.
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Who cites it
89 citing papers in PubMed, 5 syntheses or guidelines pooled it, 129 citations in OpenAlex.
- Systematic review of influenza vaccine effectiveness against laboratory-confirmed influenza among older adults living in aged care facilities.Human vaccines & immunotherapeutics · 2023Pooled it
- High Clinical Burden of Influenza Disease in Adults Aged ≥ 65 Years: Can We Do Better? A Systematic Literature Review.Advances in therapy · 2023Pooled it
- Heterogeneity in Estimates of the Impact of Influenza on Population Mortality: A Systematic Review.American journal of epidemiology · 2018Pooled it
- Acute myocardial infarction and influenza: a meta-analysis of case-control studies.Heart (British Cardiac Society) · 2015Pooled it
- Hospitalization Fatality Risk of Influenza A(H1N1)pdm09: A Systematic Review and Meta-Analysis.American journal of epidemiology · 2015Pooled it
- Modelling estimates of the burden of Respiratory Syncytial virus infection in adults and the elderly in the United Kingdom.BMC infectious diseases · 2015Trial
- Epidemiological and virological characteristics of influenza in Zhejiang Province, China: A 15-year surveillance study.Human vaccines & immunotherapeutics · 2026Article
- Waning in influenza vaccine effectiveness against influenza A(H1N1)pdm09-associated hospitalization in children in 2012/2013.Epidemiology and infection · 2025Article
- Seasonal variation in SARS-CoV-2 transmission in The Netherlands, 2020-2022: statistical evidence for an inverse association with solar radiation and temperature.Journal of the Royal Society, Interface · 2025Article
- A Bayesian spatial-temporal varying coefficients model for estimating excess deaths associated with respiratory infections.Journal of the Royal Statistical Society. Series A, (Statistics in Society) · 2025Article
- An adaptive weight ensemble approach to forecast influenza activity in an irregular seasonality context.Nature communications · 2024Article
- A post-marketing study to evaluate the safety and immunogenicity of a quadrivalent influenza split-virion vaccine in elderly people aged 60 years and older.Tropical diseases, travel medicine and vaccines · 2024Article
- Postinfectious Pulmonary Complications: Establishing Research Priorities to Advance the Field: An Official American Thoracic Society Workshop Report.Annals of the American Thoracic Society · 2024Review
- Investigation of the Impact of Childhood Immune Imprinting on Birth Year-Specific Risk of Clinical Infection During Influenza A Virus Epidemics in Hong Kong.The Journal of infectious diseases · 2023Article
- Myocardial infarction and viral triggers: what do we know by now?European heart journal supplements : journal of the European Society of Cardiology · 2023Article
- Influenza-Associated Excess Mortality by Age, Sex, and Subtype/Lineage: Population-Based Time-Series Study With a Distributed-Lag Nonlinear Model.JMIR public health and surveillance · 2023Article
- Global, regional and national estimates of influenza-attributable ischemic heart disease mortality.EClinicalMedicine · 2023Article
- Incidence of medically attended influenza and influenza virus infections confirmed by serology in Ningbo City from 2017-2018 to 2019-2020.Influenza and other respiratory viruses · 2022Article
- Estimating excess septicaemia mortality and hospitalisation burden associated with influenza in Hong Kong, 1998 to 2019.Epidemiology and infection · 2022Article
- Reconstructing antibody dynamics to estimate the risk of influenza virus infection.Nature communications · 2022Article
29 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 4 countries.
Funding
Abstract
backgroundAlthough deaths associated with laboratory-confirmed influenza virus infections are rare, the excess mortality burden of influenza estimated from statistical models may more reliably quantify the impact of influenza in a population.
methodsWe applied age-specific multiple linear regression models to all-cause and cause-specific mortality rates in Hong Kong from 1998 through 2009. The differences between estimated mortality rates in the presence or absence of recorded influenza activity were used to estimate influenza-associated excess mortality.
resultsThe annual influenza-associated all-cause excess mortality rate was 11.1 (95% confidence interval [CI], 7.2-14.6) per 100,000 person-years. We estimated an average of 751 (95% CI, 488-990) excess deaths associated with influenza annually from 1998 through 2009, with 95% of the excess deaths occurring in persons aged ≥65 years. Most of the influenza-associated excess deaths were from respiratory (53%) and cardiovascular (18%) causes. Influenza A(H3N2) epidemics were associated with more excess deaths than influenza A(H1N1) or B during the study period.
conclusionsInfluenza was associated with a substantial number of excess deaths each year, mainly among the elderly, in Hong Kong in the past decade. The influenza-associated excess mortality rates were generally similar in Hong Kong and the United States.
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