Evidence map›Paper›PMID 23045542›Full record

Trial reportCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2012

Patient navigation for breast and colorectal cancer treatment: a randomized trial.

Kevin Fiscella, Elizabeth Whitley, Samantha Hendren, Peter Raich, Sharon Humiston, Paul Winters, Pascal Jean-Pierre, Patricia Valverde, William Thorland, Ronald Epstein

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Application of patient navigation programs across the entire continuum of breast cancer care: a GRADE-assessed systematic review with meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  6. Effects of patient navigation on satisfaction with cancer care: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
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  14. Medical mistrust and patient satisfaction with mammography: the mediating effects of perceived self-efficacy among navigated African American women.Health expectations : an international journal of public participation in health care and health policy · 2015
    Trial
  15. Neighborhood factors associated with time to resolution following an abnormal breast or cervical cancer screening test.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2014
    Trial
  16. Can patient navigation improve receipt of recommended breast cancer care? Evidence from the National Patient Navigation Research Program.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2014
    Trial
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  18. Nurse navigators in early cancer care: a randomized, controlled trial.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2014
    Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kevin FiscellaDepartment of Family Medicine, University of Rochester School of Medicine & Dentistry, Rochester, New York, USA. Kevin_Fiscella@urmc.rochester.edu
Elizabeth Whitley
Samantha Hendren
Peter Raich
Sharon Humiston
Paul Winters
Pascal Jean-Pierre
Patricia Valverde
William Thorland
Ronald Epstein

Funding

RCT of Primary Care-based Patient Navigation-ActivationU01CA116924 · NCI · UNIVERSITY OF ROCHESTER · PI FISCELLA, KEVIN ANTHONY · 2005 to 2011
$4.4M
NCI NIH HHS 3U01CA116924-05SNCI NIH HHS U01 CA116924
6 · The paper itself

Abstract

backgroundThere is limited high-quality evidence about the impact of patient navigation (PN) on outcomes for patients with diagnosed cancer.

methodsWe pooled data from two sites from the national Patient Navigation Research Program. Patients (n = 438) with newly diagnosed breast (n = 353) or colorectal cancer (n = 85) were randomized to PN or usual care. Trained lay navigators met with patients randomized to PN to help them assess treatment barriers and identify resources to overcome barriers. We used intent-to-treat analysis to assess time to completion of primary treatment, psychologic distress (impact of events scale), and satisfaction (patient satisfaction with cancer-related care) within 3 months after initiation of cancer treatment.

resultsThe sample was predominantly middle-aged (mean age = 57) and female (90%); 44% were race-ethnic minorities (44%), 46% reported lower education levels, 18% were uninsured, and 9% reported a non-English primary language. The randomized groups were comparable in baseline characteristics. Primary analysis showed no statistically significant group differences in time to completion of primary cancer treatment, satisfaction with cancer-related care, or psychologic distress. Subgroup analysis showed that socially disadvantaged patients (i.e., uninsured, low English proficiency, and non-English primary language) who received PN reported higher satisfaction than those receiving usual care (all P < 0.05). Navigated patients living alone reported greater distress than those receiving usual care.

conclusionsAlthough the primary analysis showed no overall benefit, the subgroup analysis suggests that PN may improve satisfaction with care for certain disadvantaged individuals. IMPACT: PN for cancer patients may not necessarily reduce treatment time nor distress.

Indexed as

Patient NavigationAdultAgedBreast NeoplasmsColorectal NeoplasmsDepressionFemaleHumansMaleMiddle AgedPatient SatisfactionTime Factors

Identifiers

PMID23045542
PMCPMC3724524

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.