Evidence map›Paper›PMID 23044714›Full record

ReviewAnatomical record (Hoboken, N.J. : 2007)2012

The anatomical and physiological framework for vestibular prostheses.

Stephen M Highstein, Gay R Holstein

Abstract readReview
In one paragraph

Review in Anatomical record (Hoboken, N.J. : 2007), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Structural and functional changes of cortical and subcortical structures following peripheral vestibular damage in humans.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Stephen M HighsteinMarine Biological Laboratory, Woods Hole, Massachusetts 02543, USA. shighstein@mbl.edu
Gay R Holstein

Funding

Chemical Anatomy and Synaptology of Vestibulo-Sympathetic PathwaysR01DC008846 · NIDCD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HOLSTEIN, GAY R · 2008 to 2021
$5.8M
Synaptic Determinants of Vestibular Afferent DynamicsR01DC008142 · NIDCD · MARINE BIOLOGICAL LABORATORY · PI RABBITT, RICHARD D · 2009 to 2013
$2.5M
Input competition and synaptic modification during developmental remodelingR21EY019345 · NEI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HOLSTEIN, GAY · 2009 to 2010
$464k
NEI NIH HHS R21 EY019345NIDCD NIH HHS 2R01 DC008846NIDCD NIH HHS R01 DC008142NIDCD NIH HHS R01 DC008846
6 · The paper itself

Abstract

This article reviews the structure function of the vestibular system and its pathology with respect to requirements for the design and construction of a functional vestibular prosthesis. The ultimate goal of a vestibular prosthesis is to restore balance and equilibrium through direct activation of vestibular nerve fibers. An overview of the peripheral and central vestibular systems that highlights their most important functional aspects re: the design of a prosthesis is provided. Namely, the peripheral labyrinth faithfully transduces head motion and gravity in both the time and frequency domains. These signals are described in hopes that they may be prosthetically replicated. The peripheral and central connections of the vestibular nerve are also discussed in detail, as are the vestibular nuclei in the brainstem that receive VIIIth nerve innervation. Lastly, the functional effector pathways of the vestibular system, including the vestibulo-ocular, vestibulo-spinal, vestibulo-colic, vestibulo-autonomic, and vestibular efferent innervation of the labyrinth are reviewed.

Indexed as

Prostheses and ImplantsAnimalsHumansVestibule, Labyrinth

Identifiers

PMID23044714
PMCPMC4039022

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.