Evidence map›Paper›PMID 23044512›Full record

SynthesisPsycho-oncology2013

Psychosocial impact of lymphedema: a systematic review of literature from 2004 to 2011.

Mei R Fu, Sheila H Ridner, Sophia H Hu, Bob R Stewart, Janice N Cormier, Jane M Armer

Registry-linked trialOpen access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Psycho-oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07257679 (The Effects of 'Gentle Touch' in the Management of Lymphedema in Women Treated for Breast Cancer), which is not on this map. Cited by 140 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
140citing papers in PubMed, 11 pooled it
44.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07257679 phase4recruitingnot on this mapstarted 2025, after this paper: background citation

The Effects of 'Gentle Touch' in the Management of Lymphedema in Women Treated for Breast Cancer: A Preliminary Single-blind, Parallel-group Randomized Controlled Trial.

TypeinterventionalSponsorI.R.C.C.S. Fondazione Santa LuciaRan2025 to 2027Enrolled36ConditionsLymphedema, Breast CancerArmsGentle Touch (GT) Lymphatic Drainage (ANDOS technique), Passive Mobilization and Active-Assisted Exercises for the Upper Limb
3 · Its place in the literature

Who cites it

140 citing papers in PubMed, 11 syntheses or guidelines pooled it, 345 citations in OpenAlex.

  1. Interventions to improve the psychosocial outcomes of individuals with lymphedema: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. A systematic review of validated assessments methods for head and neck lymphedema.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Pooled it
  6. Pooled it
  7. Manual lymphatic drainage treatment for lymphedema: a systematic review of the literature.Journal of cancer survivorship : research and practice · 2021
    Pooled it
  8. Pooled it
  9. What are the economic burden and costs associated with the treatment of breast cancer-related lymphoedema? A systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Pooled it
  10. Pooled it
  11. Guideline
  12. Trial
  13. A pragmatic evaluation of community-based lymphoedema services for individuals at risk of, or living with, cancer-related lymphoedema.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Trial
  14. Trial
  15. Effect of exercise mode on physical function and quality of life in breast cancer-related lymphedema: a randomized trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Trial
  16. Breast cancer-related lymphedema and its treatment: how big is the financial impact?Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Trial
  17. Low-Intensity Resistance Training and Compression Garment in the Management of Breast Cancer-Related Lymphedema: Single-Blinded Randomized Controlled Trial.Journal of cancer education : the official journal of the American Association for Cancer Education · 2020
    Trial
  18. Trial
  19. Trial
  20. Trial

80 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Mei R FuNew York University College of Nursing, New York, NY 10003, USA. mf67@nyu.edu
Sheila H Ridner
Sophia H Hu
Bob R Stewart
Janice N Cormier
Jane M Armer
University of Missouri · USNew York College of Health Professions · USNew York University · USThe University of Texas MD Anderson Cancer Center · USVanderbilt University · US

Funding

Research Training and Education CoreP60MD000538 · NIMHD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI REY, MARIANO J, REY, MARIANO J · 2003 to 2017
$21.2M
Scaling Community-Clinical Linkage Models to Address Diabetes and Hypertension Disparities in the Southeastern U.S.U54MD000538 · NIMHD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI TRINH-SHEVRIN, CHAU · 2017 to 2022
$11.3M
Proinflammatory Biomarkers and Post-Breast CancerLymphedemaR21NR012288 · NINR · NEW YORK UNIVERSITY · PI FU, MEI ROSEMARY · 2011 to 2012
$452k
Managing Lymphedema in Breast Cancer SurvivorsF31NR007851 · NINR · UNIVERSITY OF MISSOURI-COLUMBIA · PI FU, MEI ROSEMARY · 2001 to 2002
$60k
NIMHD NIH HHS P60 MD000538NIMHD NIH HHS U54 MD000538NINR NIH HHS F31 NR007851NINR NIH HHS R21 NR012288
6 · The paper itself

Abstract

objectiveThis systematic review aimed to evaluate the level of evidence of contemporary peer-reviewed literature published from 2004 to 2011 on the psychosocial impact of lymphedema.

methodsEleven electronic databases were searched and 1311 articles retrieved; 23 met inclusion criteria. Twelve articles utilized qualitative methodology and 11 used quantitative methodology. An established quality assessment tool was used to assess the quality of the included studies.

resultsThe overall quality of the 23 included studies was adequate. A critical limitation of current literature is the lack of conceptual or operational definitions for the concept of psychosocial impact. Quantitative studies showed statistically significant poorer social well-being in persons with lymphedema, including perceptions related to body image, appearance, sexuality, and social barriers. No statistically significant differences were found between persons with and without lymphedema in the domains of emotional well-being (happy or sad) and psychological distress (depression and anxiety). All 12 of the qualitative studies consistently described negative psychological impact (negative self-identity, emotional disturbance, and psychological distress) and negative social impact (marginalization, financial burden, perceived diminished sexuality, social isolation, perceived social abandonment, public insensitivity, and non-supportive work environment). Factors associated with psychosocial impact were also identified.

conclusionsLymphedema has a negative psychosocial impact on affected individuals. The current review sheds light on the conceptualization and operationalization of the definitions of psychosocial impact with respect to lymphedema. Development of a lymphedema-specific instrument is needed to better characterize the impact of lymphedema and to examine the factors contributing to these outcomes in cancer and non-cancer-related populations.

Indexed as

Quality of LifeCost of IllnessFemaleHumansLeisure ActivitiesLymphedemaNeoplasmsSexualitySickness Impact ProfileSocial Supportcancerlymphedemaoncologypsychological distresspsychosocialsystematic review

Identifiers

PMID23044512
PMCPMC4153404
OpenAlexW1565361748

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.