SynthesisGeneral hospital psychiatry
Associations between health risk behaviors and symptoms of schizophrenia and bipolar disorder: a systematic review.
Synthesis in General hospital psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association between cigarette smoking and the risk of major psychiatric disorders: a systematic review and meta-analysis in depression, schizophrenia, and bipolar disorder.Frontiers in medicine · 2025Pooled it
- Multi-ancestry eQTL meta-analysis of human brain identifies candidate causal variants for brain-related traits.Nature genetics · 2022Pooled it
- Treatment response to the RENEW weight loss intervention in schizophrenia: impact of intervention setting.Schizophrenia research · 2014Trial
- Estimating the direct effects of the genetic liabilities to bipolar disorder, schizophrenia, and behavioral traits on suicide attempt using a multivariable Mendelian randomization approach.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Article
- Intensive longitudinal assessment of mobility, social activity and loneliness in individuals with severe mental illness during COVID-19.Schizophrenia (Heidelberg, Germany) · 2023Article
- Differences in body mass index trajectories of adolescent psychiatric inpatients by sex, age, diagnosis and medication: an exploratory longitudinal, mixed effects analysis.Child and adolescent mental health · 2023Article
- The Pathways to Participation (P2P) Program: A Pilot Outcomes Study.International journal of environmental research and public health · 2022Article
- Smoking Affects the Patterns of Metabolic Disorders and Metabolic Syndrome in Patients With First-Episode Drug-Naive Schizophrenia: A Large Sample Study Based on the Chinese Han Population.The international journal of neuropsychopharmacology · 2021Article
- The Optimal Length of Hospitalization for Functional Recovery of Schizophrenia Patients, a Real-World Study in Chinese People.The Psychiatric quarterly · 2019Article
- Association between lower estimated premorbid intelligence quotient and smoking behavior in patients with schizophrenia.Schizophrenia research. Cognition · 2019Article
- Latent-Profile Analysis Reveals Behavioral and Brain Correlates of Dopamine-Cognition Associations.Cerebral cortex (New York, N.Y. : 1991) · 2018Article
- Stop Turning a Blind Eye: Tobacco Smoking Among Egyptian Patients With Schizophrenia.Frontiers in psychiatry · 2018Article
- Prenatal Maternal Smoking and Tourette Syndrome: A Nationwide Register Study.Child psychiatry and human development · 2016Article
- Chair-based fidgeting and energy expenditure.BMJ open sport & exercise medicine · 2016Article
- Effects of antipsychotics, antidepressants and mood stabilizers on risk for physical diseases in people with schizophrenia, depression and bipolar disorder.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2015Article
- Smoking in schizophrenic patients: A critique of the self-medication hypothesis.World journal of psychiatry · 2015Review
- Associations between comorbid anxiety, diabetes control, and overall medical burden in patients with serious mental illness and diabetes.International journal of psychiatry in medicine · 2015Article
- Exploring the risk-factor association between depression and incident stroke: a systematic review and meta-analysis.Neuropsychiatric disease and treatment · 2015Article
- Genome-wide association study of bipolar disorder accounting for effect of body mass index identifies a new risk allele in TCF7L2.Molecular psychiatry · 2014Article
- Symptoms of anxiety and depression and risk of acute myocardial infarction: the HUNT 2 study.European heart journal · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
objectiveTo systematically review the literature to determine if health risk behaviors in patients with schizophrenia or bipolar disorder are associated with subsequent symptom burden or level of functioning.
methodUsing the PRISMA systematic review method we searched PubMed, Cochrane, PsychInfo and EMBASE databases with key words: health risk behaviors, diet, obesity, overweight, BMI, smoking, tobacco use, cigarette use, sedentary lifestyle, sedentary behaviors, physical inactivity, activity level, fitness, sitting AND schizophrenia, bipolar disorder, bipolar illness, schizoaffective disorder, severe and persistent mental illness, and psychotic to identify prospective, controlled studies of greater than 6 months duration. Included studies examined associations between sedentary lifestyle, smoking, obesity, physical inactivity and subsequent symptom severity or functional impairment in patients with schizophrenia or bipolar disorder.
resultsEight of the 2130 articles identified met inclusion criteria and included 508 patients with a health risk behavior and 825 controls. Six studies examined tobacco use, and two studies examined weight gain/obesity. Seven studies found that patients with schizophrenia or bipolar illness and at least one health risk behavior had more severe subsequent psychiatric symptoms and/or decreased level of functioning.
conclusionTobacco use and weight gain/obesity may be associated with increased severity of symptoms of schizophrenia and bipolar disorder or decreased level of functioning.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.