ArticleParasites & vectors2012
Detection of a new insect flavivirus and isolation of Aedes flavivirus in Northern Italy.
Article in Parasites & vectors, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Pooled it
- Entomological Surveillance and Arbovirus Screening in Mosquitoes from Central Morocco: First Detection of West Nile Virus in Culex pipiens from the Marrakech-Safi Region.Acta parasitologica · 2026Article
- Characterization of two novel Negevirus strains and analysis of global Negevirus distribution and host diversity.Virology journal · 2025Article
- Spatiotemporal prevalence and characterization of the lineage I insect-specific flavivirus, Quang Binh virus, isolated fromThe Journal of general virology · 2025Article
- Review
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- Development of genus-specific universal primers for the detection of flaviviruses.Virology journal · 2021Article
- Superinfection Exclusion in Mosquitoes and Its Potential as an Arbovirus Control Strategy.Viruses · 2020Review
- Viral Metagenomic Analysis ofViruses · 2020Article
- Transcriptional variation of sensory-related genes in natural populations of Aedes albopictus.BMC genomics · 2020Article
- Cell fusing agent virus (Flavivirus) infection in Aedes aegypti in Texas: seasonality, comparison by trap type, and individual viral loads.Archives of virology · 2020Article
- A survey of RNA viruses in mosquitoes from Mozambique reveals novel genetic lineages of flaviviruses and phenuiviruses, as well as frequent flavivirus-like viral DNA forms in Mansonia.BMC microbiology · 2020Article
- Arboviral screening of invasive Aedes species in northeastern Turkey: West Nile virus circulation and detection of insect-only viruses.PLoS neglected tropical diseases · 2019Article
- Co-circulation of Aedes flavivirus, Culex flavivirus, and Quang Binh virus in Shanghai, China.Infectious diseases of poverty · 2018Article
- Insect-specific viruses and their potential impact on arbovirus transmission.Current opinion in virology · 2015Review
- Insect-specific viruses detected in laboratory mosquito colonies and their potential implications for experiments evaluating arbovirus vector competence.The American journal of tropical medicine and hygiene · 2015Article
- Determinants of the population growth of the West Nile virus mosquito vector Culex pipiens in a repeatedly affected area in Italy.Parasites & vectors · 2014Article
- Lack of identification of Flaviviruses in oral and cloacal swabs from long- and short-distance migratory birds in Trentino-Alto Adige (North-eastern Italy).Virology journal · 2013Article
- Replication of West Nile virus, Rabensburg lineage in mammalian cells is restricted by temperature.Parasites & vectors · 2012Article
- Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDuring recent years, numerous novel 'insect flaviviruses' have been discovered in natural mosquito populations. In a previous study we described the presence of flavivirus DNA sequences integrated in Aedes albopictus (Asian tiger mosquito) populations from Northern Italy in 2007.
methodsDuring 2008 we collected and tested Aedes females for flavivirus presence and developed phylogenetic analysis, virus isolation, electron microscopy studies and RNAse treatments.
resultsWe detected a high prevalence of flavivirus in Ae. albopictus (77.5%). The phylogenetic analysis identified the insect flavivirus sequences as Aedes flavivirus (AEFV) recently described in Japan, and that may have been introduced in Italy travelling with the tiger mosquito. Some of these pools grew in C6/36 cells, producing cytopathic effects, and the RNase treatment results showed the presence of the detected sequences in RNA forms. Furthermore, we detected a new insect flavivirus in one pool of Aedes cinereus/geminus mosquitoes. Phylogenetic analysis of this virus shows that it forms a distinct cluster within the clade of insect flavivirus.
conclusionsThis is the first study to report a high prevalence, to describe the seasonal activity and an isolation of the insect flavivirus Aedes flavivirus in Europe. Moreover we describe the detection of a new insect flavivirus detected from Ae. cinereus mosquitoes from Italy. These flavivirus may be common, ubiquitous and diverse in nature and we discuss the implications of the insect flavivirus group in virus evolution and transmission.
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