Evidence map›Paper›PMID 23043026›Full record

ArticleBlood2012

α-1 antitrysin DAMPens GVHD.

Pavan Reddy

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Blood, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Preservation with αThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Pavan ReddyUniversity of Michigan Comprehensive Cancer Center, MI, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this issue of Blood, Brennan et al report that a noninfectious damage-associated molecular pattern (DAMP), heparan sulfate (HS),(1) aggravates graft-versus-host disease (GVHD) and that this enhanced severity can be dampened by administration of serine protease inhibitor α-1 antitrysin (AAT).(2)

Indexed as

AnimalsFemaleGraft vs Host DiseaseHematologic NeoplasmsHeparan SulfateHumansMaleStem Cell TransplantationT-LymphocytesToll-Like Receptor 4Heparan SulfateToll-Like Receptor 4

Identifiers

PMID23043026
OpenAlexW2314317325

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.