Does Candida species overgrowth protect against Clostridium difficile infection?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

15 citing papers in PubMed.

1. Infection and immunity · 2025
   Review
2. The role of gut fungi in Clostridioides difficile infection.Biomedical journal · 2024
   Review
3. Fungal and bacterial gut microbiota differ betweenMicrobiome research reports · 2024
   Article
4. Pre-colonization with the fungusmSphere · 2023
   Article
5. Characterization of the Effects of Candida Gastrointestinal Colonization on Clostridioides difficile Infection in a Murine Model.Methods in molecular biology (Clifton, N.J.) · 2022
   Article
6. Candida gut colonization, yeast species distribution, and biofilm production in Clostridioides difficile infected patients: a comparison between three populations in two different time periods.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
   Article
7. Lipid Species in the GI Tract are Increased by the Commensal FungusJournal of fungi (Basel, Switzerland) · 2020
   Article
8. The role of fungi in C. difficile infection: An underappreciated transkingdom interaction.Fungal genetics and biology : FG & B · 2019
   Review
9. Pre-colonization with the commensal fungus Candida albicans reduces murine susceptibility to Clostridium difficile infection.Gut microbes · 2018
   Article
10. Risk Factors and Outcomes for Bloodstream Infections Secondary to Clostridium difficile Infection.Antimicrobial agents and chemotherapy · 2016
    Article
11. Antibiotic susceptibility of Clostridium difficile is similar worldwide over two decades despite widespread use of broad-spectrum antibiotics: an analysis done at the University Hospital of Zurich.BMC infectious diseases · 2014
    Article
12. The human mycobiome.Cold Spring Harbor perspectives in medicine · 2014
    Review
13. Waiting for the human intestinal Eukaryotome.The ISME journal · 2013
    Article
14. Updating changes in human gut microbial communities associated withGut microbes
    Review
15. Interspecies Interactions betweenmSphere
    Article

Corrections and comments

• Commented on by
  Clostridium difficile infection and Candida colonization of the gut: is there a correlation?2014
• Comment on
  Reduced acquisition and overgrowth of vancomycin-resistant enterococci and Candida species in patients treated with fidaxomicin versus vancomycin for Clostridium difficile infection.2012

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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