Evidence map›Paper›PMID 23042564›Full record

ReviewNature reviews. Microbiology2012

Merging mythology and morphology: the multifaceted lifestyle of Proteus mirabilis.

Chelsie E Armbruster, Harry L T Mobley

Abstract readReview
In one paragraph

Review in Nature reviews. Microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 150 papers.

0numbers the graph read from it
0cells of the map it votes in
150citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

150 citing papers in PubMed.

  1. Complete genome sequence of a multidrug-resistantMicrobiology resource announcements · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Draft genome ofMicrobiology resource announcements · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Observational
  14. Article
  15. A One Health Perspective onMicroorganisms · 2026
    Review
  16. Stochastic motility energetics reveals cooperative bacterial swarming in optical tweezers.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  17. Review
  18. Article
  19. Article
  20. Article

90 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Chelsie E ArmbrusterDepartment of Microbiology and Immunology, University of Michigan Medical School, 1150 West Medical Center Drive, 5641 Medical Science Building II, Ann Arbor, Michigan 48109, USA.
Harry L T Mobley

Funding

Reciprocal Control of Motility and Adherence in UTIR01AI059722 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PEARSON, MELANIE M. · 2005 to 2024
$7.4M
E. coli virulence gene expression during clinical UTIs in womenR01DK094777 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOBLEY, HARRY L. · 2011 to 2019
$3.6M
MOLECULAR PATHOGENESIS OF E COLI UTIR01AI043363 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOBLEY, HARRY L. · 1998 to 2012
$3.4M
Vaccine to prevent E. coli urinary tract infectionR56AI043363 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOBLEY, HARRY L. · 2014 to 2014
$351k
Proteus mirabilis swarming: Initiation and role during urinary tract infectionF32AI102552 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ARMBRUSTER, CHELSIE ELIZABETH · 2012 to 2014
$156k
NIAID NIH HHS AI43363NIAID NIH HHS AI59722NIAID NIH HHS F32 AI102552NIAID NIH HHS F32AI102552NIAID NIH HHS R01 AI043363NIAID NIH HHS R01 AI059722NIAID NIH HHS R56 AI043363NIDDK NIH HHS DK94777NIDDK NIH HHS R01 DK094777
6 · The paper itself

Abstract

Proteus mirabilis, named for the Greek god who changed shape to avoid capture, has fascinated microbiologists for more than a century with its unique swarming differentiation, Dienes line formation and potent urease activity. Transcriptome profiling during both host infection and swarming motility, coupled with the availability of the complete genome sequence for P. mirabilis, has revealed the occurrence of interbacterial competition and killing through a type VI secretion system, and the reciprocal regulation of adhesion and motility, as well as the intimate connections between metabolism, swarming and virulence. This Review addresses some of the unique and recently described aspects of P. mirabilis biology and pathogenesis, and emphasizes the potential role of this bacterium in single-species and polymicrobial urinary tract infections.

Indexed as

Bacterial AdhesionBacterial ProteinsBacterial Secretion SystemsCatheter-Related InfectionsGene Expression Regulation, BacterialGene Transfer, HorizontalHumansImmune EvasionProteus InfectionsProteus mirabilisUrinary Tract InfectionsVirulence FactorsBacterial ProteinsBacterial Secretion SystemsVirulence Factors

Identifiers

PMID23042564
PMCPMC3621030

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.