ReviewChild and adolescent psychiatric clinics of North America2012
The neural effects of psychotropic medications in children and adolescents.
Review in Child and adolescent psychiatric clinics of North America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 32 citations in OpenAlex.
- Trial
- Causal Analyses of Associations Between Brain Structure and Suicide Attempt in Adulthood and Late Childhood.JAACAP open · 2025Article
- Neuroimaging as a Tool for Advancing Pediatric Psychopharmacology.Paediatric drugs · 2025Review
- Updates in the Assessment and Management of Agitation.Focus (American Psychiatric Publishing) · 2023Article
- Functional connectome differences in individuals with hallucinations across the psychosis continuum.Scientific reports · 2021Article
- Basal ganglia volume and shape in anorexia nervosa.Appetite · 2020Article
- White matter disruptions in patients with bipolar disorder.European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2018Article
- Dosing and Monitoring: Children and Adolescents.Psychopharmacology bulletin · 2018Review
- Treatment of psychiatric symptoms among offspring of parents with bipolar disorder.Current treatment options in psychiatry · 2017Article
- Psychotropic medication use in autism spectrum disorders may affect functional brain connectivity.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2017Article
- Hyperactivation in Cognitive Control and Visual Attention Brain Regions During Emotional Interference in Adolescent Depression.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2017Article
- Updated report on tools to measure outcomes of clinical trials in fragile X syndrome.Journal of neurodevelopmental disorders · 2017Review
- Atypical cortical gyrification in adolescents with histories of heavy prenatal alcohol exposure.Brain research · 2015Article
- Brain Structural Effects of Psychopharmacological Treatment in Bipolar Disorder.Current neuropharmacology · 2015Review
- Abnormal deactivation of the inferior frontal gyrus during implicit emotion processing in youth with bipolar disorder: attenuated by medication.Journal of psychiatric research · 2014Article
- Psychotropic Medications and Their Effect on Brain Volumes in Childhood Psychopathology.Child & adolescent psychopharmacology news · 2014Article
- Long-term impacts of adolescent risperidone treatment on behavioral responsiveness to olanzapine and clozapine in adulthood.Progress in neuro-psychopharmacology & biological psychiatry · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Little is known about the neurobiological effects of psychotropic medications used in the treatment of children and adolescents diagnosed with a psychiatric disorder. This review provides a synopsis of the literature demonstrating the neural effects associated with exposure to psychotropic medication in youth using multimodal neuroimaging. The article concludes by illustrating how, taken together, these studies suggest that pharmacological interventions during childhood do indeed affect brain structure and function in a detectable manner, and the effects appear to be ameliorative.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.