ReviewBest practice & research. Clinical anaesthesiology2012
Delirium: is sleep important?
Review in Best practice & research. Clinical anaesthesiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 95 citations in OpenAlex.
- Electroencephalography of mechanically ventilated patients at high risk of delirium.Acta neurologica Scandinavica · 2021Trial
- A Personalized, Symptom-Based Approach to Boost Research Participation in Hospitalized Older Adults.Journal of the American Geriatrics Society · 2026Article
- High-resolution monitoring reveals fragmented 24-hour light exposure in intensive care units.Critical care (London, England) · 2026Observational
- Glymphatic dysfunction: a unifying hypothesis for delirium.Nature reviews. Neurology · 2026Review
- Promoting Sleep for Neurology Inpatients: The Value of Routine Overnight Vital Signs.Neurology. Clinical practice · 2025Article
- From Acute Confusion to Chronic Decline: The Cognitive Impact of Delirium in Older Adults.Rhode Island medical journal (2013) · 2025Review
- Clinical and intracranial electrophysiological signatures of post-operative and post-ictal delirium.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2025Article
- Efficacy of a melatonin receptor agonist and orexin receptor antagonists in preventing delirium symptoms in the olderly patients with stroke: a retrospective study.Journal of pharmaceutical health care and sciences · 2024Article
- Causal Associations Between Sleep Traits and Delirium: A Bidirectional Two-Sample Mendelian Randomization Study.Nature and science of sleep · 2024Article
- Association and prediction of subjective sleep quality and postoperative delirium during major non-cardiac surgery: a prospective observational study.BMC anesthesiology · 2023Observational
- Sleep staging in the ICU with heart rate variability and breathing signals. An exploratory cross-sectional study using deep neural networks.Frontiers in network physiology · 2023Article
- Sleep and critical illness: a review.Frontiers in medicine · 2023Review
- Evaluation of Nonpharmacologic Interventions and Sleep Outcomes in Hospitalized Medical and Surgical Patients: A Nonrandomized Controlled Trial.JAMA network open · 2022Article
- Practices and Patterns of Hourly Neurochecks: Analysis of 8,936 Patients With Neurological Injury.Journal of intensive care medicine · 2022Article
- Less pharmacotherapy is more in delirium.Intensive care medicine · 2022Article
- Incidence, Associated Factors, and Outcome of Delirium among Patients Admitted to ICUs in Oman.Critical care research and practice · 2022Article
- Delirium Variability is Influenced by the Sound Environment (DEVISE Study): How Changes in the Intensive Care Unit soundscape affect delirium incidence.Journal of medical systems · 2021Article
- Cardiovascular and Pre-Frailty Risk Assessment during Shelter-In-Place Measures Based on Multimodal Biomarkers Collected from Smart Telemedical Wearables.Journal of clinical medicine · 2021Article
- Effects of Preoperative Anxiety on Postoperative Delirium in Elderly Patients Undergoing Elective Orthopedic Surgery: A Prospective Observational Cohort Study.Clinical interventions in aging · 2021Observational
- Hospital-level intensive care unit admission for patients with isolated blunt abdominal solid organ injury.The journal of trauma and acute care surgery · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Delirium and poor sleep quality are common and often co-exist in hospitalised patients. A link between these disorders has been hypothesised but whether this link is a cause-and-effect relationship or simply an association resulting from shared mechanisms is yet to be determined. Potential shared mechanisms include: abnormalities of neurotransmitters, tissue ischaemia, inflammation and sedative exposure. Sedatives, while decreasing sleep latency, often cause a decrease in slow wave sleep and stage rapid eye movement (REM) sleep and therefore may not provide the same restorative properties as natural sleep. Mechanical ventilation, an important cause of sleep disruption in intensive care unit (ICU) patients, may lead to sleep disruption not only from the discomfort of the endotracheal tube but also as a result of ineffective respiratory efforts and by inducing central apnoea events if not properly adjusted for the patient's physiologic needs. When possible, efforts should be made to optimise the patient-ventilator interaction to minimise sleep disruptions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.