ArticleGenome research2013
A calibrated human Y-chromosomal phylogeny based on resequencing.
Article in Genome research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.
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Who cites it
75 citing papers in PubMed, 153 citations in OpenAlex.
- Multiple southward migrations of Neolithic Chinese farmers into Southeast Asia revealed from large-scale Y-chromosome sequences.Science advances · 2026Article
- Resolving the source of branch length variation in the Y chromosome phylogeny.Genome biology · 2025Article
- Multiple Human Population Movements and Cultural Dispersal Events Shaped the Landscape of Chinese Paternal Heritage.Molecular biology and evolution · 2024Article
- Application of Targeted Y-Chromosomal Capture Enrichment to Increase the Resolution of Native American Haplogroup Q.Human mutation · 2024Article
- Multiple founding paternal lineages inferred from the newly-developed 639-plex Y-SNP panel suggested the complex admixture and migration history of Chinese people.Human genomics · 2023Article
- Y-chromosome target enrichment reveals rapid expansion of haplogroup R1b-DF27 in Iberia during the Bronze Age transition.Scientific reports · 2022Article
- Editorial: Role of Y Chromosome in Molecular Anthropology, Forensics, and Genetic Genealogy.Frontiers in genetics · 2022Article
- Human-Mediated Admixture and Selection Shape the Diversity on the Modern Swine (Sus scrofa) Y Chromosomes.Molecular biology and evolution · 2021Article
- Article
- Mutation Rate Variability across Human Y-Chromosome Haplogroups.Molecular biology and evolution · 2021Article
- A Southeast Asian origin for present-day non-African human Y chromosomes.Human genetics · 2021Article
- Sex-biased patterns shaped the genetic history of Roma.Scientific reports · 2020Article
- Y-Chromosome Variation in Southern African Khoe-San Populations Based on Whole-Genome Sequences.Genome biology and evolution · 2020Article
- Human Y Chromosome Exerts Pleiotropic Effects on Susceptibility to Atherosclerosis.Arteriosclerosis, thrombosis, and vascular biology · 2019Article
- A Rare Deep-Rooting D0 African Y-Chromosomal Haplogroup and Its Implications for the Expansion of Modern Humans Out of Africa.Genetics · 2019Article
- Whole-genome sequence analysis of a Pan African set of samples reveals archaic gene flow from an extinct basal population of modern humans into sub-Saharan populations.Genome biology · 2019Article
- Genetic diversities and phylogenetic analyses of three Chinese main ethnic groups in southwest China: A Y-Chromosomal STR study.Scientific reports · 2018Article
- IMPUTOR: Phylogenetically Aware Software for Imputation of Errors in Next-Generation Sequencing.Genome biology and evolution · 2018Article
- Whole Y-chromosome sequences reveal an extremely recent origin of the most common North African paternal lineage E-M183 (M81).Scientific reports · 2017Article
- Next Generation Sequencing Plus (NGS+) with Y-chromosomal Markers for Forensic Pedigree Searches.Scientific reports · 2017Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
Abstract
We have identified variants present in high-coverage complete sequences of 36 diverse human Y chromosomes from Africa, Europe, South Asia, East Asia, and the Americas, representing eight major haplogroups. After restricting our analysis to 8.97 Mb of the unique male-specific Y sequence, we identified 6662 high-confidence variants, including single-nucleotide polymorphisms (SNPs), multi-nucleotide polymorphisms (MNPs), and indels. We constructed phylogenetic trees using these variants, or subsets of them, and recapitulated the known structure of the tree. Assuming a male mutation rate of 1 × 10(-9) per base pair per year, the time depth of the tree (haplogroups A3-R) was ~101,000-115,000 yr, and the lineages found outside Africa dated to 57,000-74,000 yr, both as expected. In addition, we dated a striking Paleolithic male lineage expansion to 41,000-52,000 yr ago and the node representing the major European Y lineage, R1b, to 4000-13,000 yr ago, supporting a Neolithic origin for these modern European Y chromosomes. In all, we provide a nearly 10-fold increase in the number of Y markers with phylogenetic information, and novel historical insights derived from placing them on a calibrated phylogenetic tree.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.