Evidence map›Paper›PMID 23037940›Full record

ArticleAngewandte Chemie (International ed. in English)2012

Isotope-based analysis of modified tRNA nucleosides correlates modification density with translational efficiency.

Caterina Brandmayr, Mirko Wagner, Tobias Brückl, Daniel Globisch, David Pearson, Andrea Christa Kneuttinger, Veronika Reiter, Antje Hienzsch, Susanne Koch, Ines Thoma and 5 more

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Advancements in pseudouridine modifying enzyme and cancer.Frontiers in cell and developmental biology · 2024
    Review
  3. Article
  4. tRNA modification profiles in obligate and moderate thermophilic bacilli.Extremophiles : life under extreme conditions · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. The Profile and Dynamics of RNA Modifications in Animals.Chembiochem : a European journal of chemical biology · 2017
    Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Caterina BrandmayrCenter for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, Butenandtstrasse 5-13, 81377 Munich, Germany.
Mirko Wagner
Tobias Brückl
Daniel Globisch
David Pearson
Andrea Christa Kneuttinger
Veronika Reiter
Antje Hienzsch
Susanne Koch
Ines Thoma
Peter Thumbs
Stylianos Michalakis
Markus Müller
Martin Biel
Thomas Carell

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Useful diversity: Quantification of modified tRNA nucleobases in different murine and porcine tissues reveals a tissue-specific overall modification content. The modification content correlates with rates of protein synthesis in vitro, suggesting a direct link between tRNA modification levels and tissue-specific translational efficiency.

Indexed as

AnimalsCarbon IsotopesChromatography, LiquidDeuteriumIsotope LabelingMass SpectrometryMiceNitrogen IsotopesNucleosidesRibonuclease, PancreaticRNA, TransferSwineCarbon IsotopesDeuteriumNitrogen IsotopesNucleosidesRibonuclease, PancreaticRNA, Transfer

Identifiers

PMID23037940
PMCPMC3533783

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.