ArticlePlant physiology2012
Disruption of abscisic acid signaling constitutively activates Arabidopsis resistance to the necrotrophic fungus Plectosphaerella cucumerina.
Article in Plant physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
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Who cites it
67 citing papers in PubMed, 156 citations in OpenAlex.
- Carbohydrate-active enzymes from a core root mycobiota member enable infection of multiple plant hosts.Nature microbiology · 2026Article
- Winning by Losing: Exploiting Modified Plant Susceptibility Genes to Counteract Necrotrophic Fungal Pathogens.Plant biotechnology journal · 2025Review
- Abscisic Acid MetabolizingPlants (Basel, Switzerland) · 2025Article
- Nitric Oxide Mitigates the Deleterious Effects Caused by Infection ofPlants (Basel, Switzerland) · 2024Article
- The RIN4-like/NOI proteins NOI10 and NOI11 modulate the response to biotic stresses mediated by RIN4 in Arabidopsis.Plant cell reports · 2024Article
- Abscisic-acid-responsiveFrontiers in plant science · 2024Article
- Mitogen-activated protein kinase phosphatase 1 controls broad spectrum disease resistance inFrontiers in plant science · 2024Article
- Small RNAs: Efficient and miraculous effectors that play key roles in plant-microbe interactions.Molecular plant pathology · 2023Review
- Signals and Their Perception for Remodelling, Adjustment and Repair of the Plant Cell Wall.International journal of molecular sciences · 2023Review
- Gene enrichment and co-expression analysis shed light on transcriptional responses to Ralstonia solanacearum in tomato.BMC genomics · 2023Article
- Plant Cell Wall Integrity Perturbations and Priming for Defense.Plants (Basel, Switzerland) · 2022Review
- Signal Transduction in Cereal Plants Struggling with Environmental Stresses: From Perception to Response.Plants (Basel, Switzerland) · 2022Review
- Phosphate-induced resistance to pathogen infection in Arabidopsis.The Plant journal : for cell and molecular biology · 2022Article
- β-aminobutyric acid (BABA)-induced resistance to tobacco black shank in tobacco (Nicotiana tabacum L.).PloS one · 2022Article
- Defence Responses Associated with Elicitor-Induced, Cultivar-Associated Resistance to Latania Scale in Kiwifruit.Plants (Basel, Switzerland) · 2021Article
- Non-Targeted Metabolite Profiling Reveals Host Metabolomic Reprogramming during the Interaction of Black Pepper withInternational journal of molecular sciences · 2021Article
- Spider mite egg extract modifies Arabidopsis response to future infestations.Scientific reports · 2021Article
- Biocontrol Potential ofJournal of fungi (Basel, Switzerland) · 2021Article
- GhMYB4 downregulates lignin biosynthesis and enhances cotton resistance to Verticillium dahliae.Plant cell reports · 2021Article
- Responses to Drought Stress Modulate the Susceptibility toPlants (Basel, Switzerland) · 2021Article
7 more citing papers are in PubMed but not listed here.
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
Plant resistance to necrotrophic fungi is regulated by a complex set of signaling pathways that includes those mediated by the hormones salicylic acid (SA), ethylene (ET), jasmonic acid (JA), and abscisic acid (ABA). The role of ABA in plant resistance remains controversial, as positive and negative regulatory functions have been described depending on the plant-pathogen interaction analyzed. Here, we show that ABA signaling negatively regulates Arabidopsis (Arabidopsis thaliana) resistance to the necrotrophic fungus Plectosphaerella cucumerina. Arabidopsis plants impaired in ABA biosynthesis, such as the aba1-6 mutant, or in ABA signaling, like the quadruple pyr/pyl mutant (pyr1pyl1pyl2pyl4), were more resistant to P. cucumerina than wild-type plants. In contrast, the hab1-1abi1-2abi2-2 mutant impaired in three phosphatases that negatively regulate ABA signaling displayed an enhanced susceptibility phenotype to this fungus. Comparative transcriptomic analyses of aba1-6 and wild-type plants revealed that the ABA pathway negatively regulates defense genes, many of which are controlled by the SA, JA, or ET pathway. In line with these data, we found that aba1-6 resistance to P. cucumerina was partially compromised when the SA, JA, or ET pathway was disrupted in this mutant. Additionally, in the aba1-6 plants, some genes encoding cell wall-related proteins were misregulated. Fourier transform infrared spectroscopy and biochemical analyses of cell walls from aba1-6 and wild-type plants revealed significant differences in their Fourier transform infrared spectratypes and uronic acid and cellulose contents. All these data suggest that ABA signaling has a complex function in Arabidopsis basal resistance, negatively regulating SA/JA/ET-mediated resistance to necrotrophic fungi.
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