Evidence map›Paper›PMID 23036920›Full record

ArticleJournal of substance abuse treatment2012

Concurrent group treatment for hepatitis C: implementation and outcomes in a methadone maintenance treatment program.

Melissa R Stein, Irene J Soloway, Karen S Jefferson, Robert J Roose, Julia H Arnsten, Alain H Litwin

Abstract read
In one paragraph

Article in Journal of substance abuse treatment, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Article
  9. International journal of environmental research and public health · 2019
    Article
  10. Hepatitis C elimination among people who inject drugs: Challenges and recommendations for action within a health systems framework.Liver international : official journal of the International Association for the Study of the Liver · 2019
    Review
  11. Review
  12. Article
  13. Building a Hepatitis C Clinical Program: Strategies to Optimize Outcomes.Current treatment options in infectious diseases · 2018
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Melissa R SteinDivision of General Internal Medicine, Department of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York, USA.
Irene J Soloway
Karen S Jefferson
Robert J Roose
Julia H Arnsten
Alain H Litwin

Funding

Intensive Models of HCV Care for Injection Drug UsersR01DA034086 · NIDA · CLEMSON UNIVERSITY · PI LITWIN, ALAIN HARRIS · 2012 to 2016
$3.7M
CLINICAL ADDICTION RESEARCH AND EDUCATION (CARE) PROGRAMR25DA014551 · NIDA · MONTEFIORE MEDICAL CENTER (BRONX, NY) · PI ARNSTEN, JULIA H. · 2002 to 2005
$1.3M
Directly Observed Hepatitis C Treatment in Methadone ClinicsK23DA022454 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI LITWIN, ALAIN HARRIS · 2008 to 2012
$904k
NIDA NIH HHS K23 DA022454NIDA NIH HHS R01 DA034086NIDA NIH HHS R25 DA014551NIDA NIH HHS R25 DA 14551PHS HHS P30 A151519PHS HHS U50 CCU22419201
6 · The paper itself

Abstract

Chronic hepatitis C virus (HCV) infection is highly prevalent among current and former drug users. However, the minority of patients enrolled in drug treatment programs have initiated HCV treatment. New models are needed to overcome barriers to care. In this retrospective study, we describe the implementation and outcomes of 42 patients treated in a concurrent group treatment (CGT) program. Patients participated in weekly provider-led group treatment sessions which included review of side effects; discussion of adherence and side effect management; administration of interferon injections; brief physical examination; and ended with brief meditation. Of the first 27 patients who initiated CGT, 42% achieved a sustained viral response. In addition, 87% (13/15) of genotype-1 infected patients treated with direct acting antiviral agent achieved an undetectable viral load at 24 weeks. The CGT model may be effective in overcoming barriers to treatment and improving adherence and outcomes among patients enrolled in drug treatment programs.

Indexed as

AdultAntiviral AgentsDrug Therapy, CombinationFemaleGenotypeHepacivirusHepatitis C, ChronicHeroin DependenceHumansInterferon-alphaMaleMedication AdherenceMethadoneMiddle AgedOpiate Substitution TreatmentPolyethylene GlycolsAntiviral AgentsInterferon-alphaMethadonepeginterferon alfa-2aPolyethylene GlycolsRecombinant ProteinsRibavirin

Identifiers

PMID23036920
PMCPMC3505858

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.