ArticleArthritis research & therapy2012
Chondrocalcinosis is common in the absence of knee involvement.
Article in Arthritis research & therapy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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21 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.
- Which are the most frequently involved peripheral joints in calcium pyrophosphate crystal deposition at imaging? A systematic literature review and meta-analysis by the OMERACT ultrasound - CPPD subgroup.Frontiers in medicine · 2023Pooled it
- Prevalence of Radiographic Knee and Wrist Chondrocalcinosis in Adana Province, Türkiye: A Hospital-Based Retrospective Study.Archives of rheumatology · 2026Article
- Diagnosis of calcium pyrophosphate crystal deposition disease by ultrasonography: how many and which sites should be scanned?Rheumatology (Oxford, England) · 2024Article
- A Narrative Review of Chondrocalcinosis: Clinical Presentation, Diagnosis, and Therapies.Cureus · 2024Review
- Calcium pyrophosphate deposition disease: historical overview and potential gaps.Frontiers in medicine · 2024Review
- Diagnosis and Treatment of Calcium Pyrophosphate Deposition (CPPD) Disease: A Review.Open access rheumatology : research and reviews · 2023Review
- Article
- Chondrocalcinosis: Advances in Diagnostic Imaging.Current rheumatology reports · 2021Review
- A Phage Display-Identified Short Peptide Capable of Hydrolyzing Calcium Pyrophosphate Crystals-The Etiological Factor of Chondrocalcinosis.Molecules (Basel, Switzerland) · 2021Article
- A critical review of the available evidence on the diagnosis and clinical features of CPPD: do we really need imaging?Clinical rheumatology · 2021Review
- The role of Interleukin-1 receptor antagonist as a treatment option in calcium pyrophosphate crystal deposition disease.Molecular biology reports · 2021Review
- Association between serum zinc and copper concentrations and copper/zinc ratio with the prevalence of knee chondrocalcinosis: a cross-sectional study.BMC musculoskeletal disorders · 2020Article
- Prevalence of chondrocalcinosis in a Mexican tertiary care institution of musculoskeletal disorders.Clinical rheumatology · 2019Article
- Subclinical crystal arthropathy: a silent contributor to inflammation and functional disability in knees with osteoarthritis-an ultrasound study.Journal of medical ultrasonics (2001) · 2019Article
- Non-union rate of type II and III odontoid fractures in CPPD versus a control population.Skeletal radiology · 2018Article
- Dose-response relationship between lower serum magnesium level and higher prevalence of knee chondrocalcinosis.Arthritis research & therapy · 2017Article
- The prevalence of chondrocalcinosis of the symphysis pubis on CT scan and correlation with calcium pyrophosphate dihydrate crystal deposition disease.Clinical rheumatology · 2016Article
- Systematic review and quality analysis of emerging diagnostic measures for calcium pyrophosphate crystal deposition disease.RMD open · 2016Article
- Imaging of calcium pyrophosphate deposition disease.Current rheumatology reports · 2015Review
- Rapidly destructive inflammatory arthritis of the hip.Case reports in rheumatology · 2014Article
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6 authors at 3 institutions in 2 countries.
Funding
Abstract
introductionWe aimed to describe the distribution of radiographic chondrocalcinosis (CC) and to examine whether metacarpophalangeal joint (MCPJ) calcification and CC at other joints occurs in the absence of knee involvement.
methodsThis was a cross-sectional study embedded in the Genetics of Osteoarthritis and Lifestyle study (GOAL). All participants (n = 3,170) had radiographs of the knees, hands, and pelvis. These were scored for radiographic changes of osteoarthritis (OA), for CC at knees, hips, symphysis pubis, and wrists, and for MCPJ calcification. The prevalence of MCPJ calcification and CC overall, at each joint, and in the presence or absence of knee involvement, was calculated.
resultsThe knee was the commonest site of CC, followed by wrists, hips, and symphysis pubis. CC was more likely to be bilateral at knees and wrists but unilateral at hips. MCPJ calcification was usually bilateral, and less common than CC at knees, hips, wrists, and symphysis pubis. Unlike that previously reported, CC commonly occurred without any knee involvement; 44.4% of wrist CC, 45.9% of hip CC, 45.5% of symphysis pubis CC, and 31.3% of MCPJ calcification occurred in patients without knee CC. Those with meniscal or hyaline articular cartilage CC had comparable ages (P = 0.21), and neither preferentially associated with fibrocartilage CC at distant joints.
conclusionsCC visualized on a plain radiograph commonly occurs at other joints in the absence of radiographic knee CC. Therefore, knee radiographs alone are an insufficient screening test for CC. This has significant implications for clinical practice, for epidemiologic and genetic studies of CC, and for the definition of OA patients with coexistent crystal deposition.
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